Mohammad Hassan SHEHATA
Assistant Professor

現在の研究テーマ（current research project）

Human beings shape their life according to the information they learn from the various life experiences. The memories of each piece of information form the building blocks for complete person’s knowledge. Newly learned information interacts with some of the old ones either by strengthening or weakening them. In the past few decades, research was focused on how new memories are formed in our brain. However, little is known about how memories are weakened or completely forgotten. The answer to this question is not only important to prevent losing our valuable memories, but also to enhance removal of anxious painful memories which is useful to treat psychological disorders, such as post-traumatic stress disorder (PTSD). My research is about the role of protein degradation mechanisms, specifically autophagy, in memory destabilization.

抱負（ambitious future plan）

My vision is to add or helping those adding an important stone in the building of science that is useful for the life of human beings.

専門分野 （background scientific field）

2007-2011: Ph.D., Department of Biochemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Japan.
1996-2001: Bachelor of Pharmaceutical Sciences, Faculty of Pharmacy, Cairo University, Egypt.

略 歴（personal history）

2006-Now: Assistant Professor, Department of Biochemistry, Faculty of Medicine, University of Toyama, Toyama, Japan.
2005-2006: Teaching Assistant, Organic chemistry and Biochemistry department, Faculty of Pharmacy, German University in Cairo, Egypt.
2001-Now: Teaching Assistant, Biochemistry department, Faculty of Pharmacy, Cairo University, Egypt.

業 績（publications）

• Takasawa A., Kato I., Takasawa K., Ishii Y., Yoshida T., Shehata M. H., Kawaguchi H., Mohafez O. M. M., Sasahara M., and Hiraga K.
  Mutation-, aging-, and gene dosage-dependent accumulation of neuroserpin (G392E) in endoplasmic reticula and lysosomes of neurons in transgenic mice. J. Biol. Chem. 283, 35606-35613.
• Kawaguchi H., Okamoto S., Sikdar D., Kume A., Li F., Mohafez O.M., Shehata M.H., and Hiraga K.
  Genomic organization of regions that regulate chicken glycine decarboxylase gene transcription: physiological and pathological implications. Gene 432, 7-18.
• Yu Da-Yong, Zhao Qing-Li, Wei Zheng-Li, Shehata M, Kondo Takashi.
  Enhancement of hyperthermia-induced apoptosis by sanazole in human lymphoma U937 cells.　International Journal of Hyperthermia, Volume 25, Number 5, August, pp. 364-373(10).9
• Takashi Kondo, Toru Yoshida, Ryohei Ogawa, Mariame A. Hassan, Yukihiro Furusawa, Qing-Li Zhao, Akihiko Watanabe, Akihiro Morii, Loreto B. Feril Jr., Katsuro Tachibana, Hiroshi Kitagawa, Yoshiaki Tabuchi, Ichiro Takasaki, Mohammad H. Shehata, Nobuki Kudo and Kazuhiro Tsukada.
  Low-intensity ultrasound adjuvant therapy: enhancement of doxorubicin-induced cytotoxicity and the acoustic mechanisms involved. Journal of Medical Ultrasonics, Volume 36, Number 2 / June, pp. 61-68.
• Shehata M, Matsumura H, Okubo-Suzuki R, Ohkawa N, Inokuchi K.
  Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. Journal of Neuroscience. Jul 25;32(30):10413-22. doi: 10.1523/JNEUROSCI.4533-11.2012.

趣味・特技（hobby, specialty）

Soccer, Computer Graphics, Social Activities

アピールポイントなど特に記載したいこと（appeal to the audiences）

“Creativity is just connecting things. When you ask creative people how they did something, they feel a little guilty because they didn't really do it, they just saw something. It seemed obvious to them after a while. That's because they were able to connect experiences they've had and synthesize new things.” Steve Jobs

“Your work is going to fill a large part of your life, and the only way to be truly satisfied is to do what you believe is great work. And the only way to do great work is to love what you do. If you haven't found it yet, keep looking. Don't settle. As with all matters of the heart, you'll know when you find it.” Steve Jobs