富山大学大学院医学薬学研究部(医学)

先進がん免疫治療学講座

業績

 

関連論文

  1. 1.Hamana H, Shitaoka K, Kishi H, Ozawa T, Muraguchi A. A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells. Biochem Biophys Res Commun. 2016 Jun 10;474(4):709-714.


  1. 2.Piao X, Ozawa T, Hamana H, Shitaoka K, Jin A, Kishi H, Muraguchi A. TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo. OncoImmunology. 2016 May 4;5(5):e1131380.


  1. 3.Mou Z, Li J, Boussoffara T, Kishi H, Hamana H, Ezzati P, Hu C, Yi W, Liu D, Khadem F, Okwor I, Jia P, Shitaoka K, Wang S, Ndao M, Petersen C, Chen J, Rafati  S, Louzir H, Muraguchi A, Wilkins JA, Uzonna JE. Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells. Sci Transl Med. 2015 Oct 21;7(310):310ra167.


  1. 4.Kobayashi E, Mizukoshi E, Kishi H, Ozawa T, Hamana H, Nagai T, Nakagawa H, Jin A, Kaneko S, Muraguchi A. A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days. Nat Med. 2013 Nov;19(11):1542-1546.

2018


[1]

Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases.

Okumura M, Ozawa T, Hamana H, Norimatsu Y, Tsuda R, Kobayashi E, Shinoda K, Taki H, Tobe K, Imura J, Sugiyama E, Kishi H, Muraguchi A.

Eur J Immunol. 2018 Jul 10. doi: 10.1002/eji.201747381. [Epub ahead of print]

PMID: 29989658


[2]

Introduction of Genetically-Modified CD3ζ Improves Proliferation and Persistence of Antigen-specific CTLs.

Miyao K, Terakura S, Okuno S, Julamanee J, Watanabe K, Hamana H, Kishi H, Sakemura R, Koyama D, Goto T, Nishida T, Murata M, Kiyoi H.

Cancer Immunol Res. 2018 Apr 13. pii: canimm.0538.2017. doi: 10.1158/2326-6066.CIR-17-0538. [Epub ahead of print] PMID: 29653982


[3]

Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis.

Shitaoka K, Hamana H, Kishi H, Hayakawa Y, Kobayashi E, Sukegawa K, Piao X, Lyu F, Nagata T, Sugiyama D, Nishikawa H, Tanemura A, Katayama I, Murahashi M, Takamatsu Y, Tani K, Ozawa T, Muraguchi A.

Cancer Immunol Res. 2018 Apr;6(4):378-388. doi: 10.1158/2326-6066.CIR-17-0489. Epub 2018 Feb 23.PubMed PMID: 29475880.


[4]

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.

Espinoza JL, Elbadry MI, Chonabayashi K, Yoshida Y, Katagiri T, Harada K, Nakagawa N, Zaimoku Y, Imi T, Hassanein HA, Khalifa A Noreldin A, Takenaka K, Akashi K, Hamana H, Kishi H, Akatsuka Y, Nakao S.

Blood Adv. 2018 Feb 27;2(4):390-400. doi: 10.1182/bloodadvances.2017013342. PubMed PMID: 29472446; PubMed Central PMCID: PMC5858477.


[5]

Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4(+) T cells expressing converged T-cell receptor genes in vitro.

Tsuruta M, Ueda S, Yew PY, Fukuda I, Yoshimura S, Kishi H, Hamana H, Hirayama M, Yatsuda J, Irie A, Senju S, Yuba E, Kamba T, Eto M, Nakayama H, Nishimura Y.

OncoImmunology. 2018 Jan 5;7(4):e1415687. doi: 10.1080/2162402X.2017.1415687.eCollection 2018. PubMed PMID: 29632734; PubMed Central PMCID: PMC5889196.


2017


[1]

Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals.

Miyama T, Kawase T, Kitaura K, Chishaki R, Shibata M, Oshima K, Hamana H, Kishi H, Muraguchi A, Kuzushima K, Saji H, Shin-I T, Suzuki R, Ichinohe T

Sci Rep. 2017 Jun 16;7(1):3663. doi:10.1038/s41598-017-03855-x. PubMed PMID: 28623251; PubMed Central PMCID: PMC5473819.