富山大学大学院医学薬学研究部皮膚科学講座 富山大学 TOP 皮膚科学 TOP

皮膚科学TOP|富山大学大学院医学薬学研究部皮膚科学講座ごあいさつ|富山大学大学院医学薬学研究部皮膚科学講座スタッフ紹介|富山大学大学院医学薬学研究部皮膚科学講座診療案内|富山大学大学院医学薬学研究部皮膚科学講座研修医の方へ|富山大学大学院医学薬学研究部皮膚科学講座お問い合せ|富山大学大学院医学薬学研究部皮膚科学講座
研究内容|富山大学大学院医学薬学研究部皮膚科学講座
研究テーマ|富山大学大学院医学薬学研究部皮膚科学講座
皮膚アレルギー免疫解析グループ|富山大学大学院医学薬学研究部皮膚科学講座
1)炎症性サイトカインと皮膚疾患 ―特にアトピー性皮膚炎との関連―|富山大学大学院医学薬学研究部皮膚科学講座
炎症性サイトカインと皮膚疾患 ―特にアトピー性皮膚炎との関連―|富山大学大学院医学薬学研究部皮膚科学講座 アトピー性皮膚炎患者の血清中や病変部においてMIF は強く発現し、その発現レベルは皮膚症状の改善に伴い低下する。また、MIFは病変部局所にとどまらず、全身のサイトカインネットワークの中でアトピー性皮膚炎の病態に関与している。
2)炎症性サイトカインと紫外線の皮膚に及ぼす影響|富山大学大学院医学薬学研究部皮膚科学講座
3)水疱性類天疱瘡の発症メカニズムに関する研究|富山大学大学院医学薬学研究部皮膚科学講座
角化症解析グループ|富山大学大学院医学薬学研究部皮膚科学講座
1)表皮角化細胞の分化増殖に関する研究|富山大学大学院医学薬学研究部皮膚科学講座
表皮角化細胞の分化増殖に関する研究|富山大学大学院医学薬学研究部皮膚科学講座 これまでに我々が同定したfused-S100蛋白質のひとつであるHornerinを中心に、未だ十分に機能が解明されていないTCHHL1やFLG2などの角化における役割や皮膚疾患との関連について研究を行っている。

2)角化誘導機序の解明と治療への応用|富山大学大学院医学薬学研究部皮膚科学講座
漢方解析グループ|富山大学大学院医学薬学研究部皮膚科学講座

本学の特徴の一つである漢方治療のエビデンスを確立するため、漢方に関する臨床および基礎研究を行っている。これまでに、アトピー性皮膚炎に対する漢方薬の効果をSCORADや血清TARC値など他覚的指標により評価し、苔癬化病変が主体の患者に桂枝茯苓丸が有効であることを明らかにした。また、桂枝茯苓丸に含まれるペオニフロリンが血管内皮細胞から産生される炎症性サイトカインを抑制することや、紫雲膏に含まれるアルカニンが熱ショック蛋白質を介して細胞保護機能関連遺伝子の発現を誘導し、表皮角化細胞における紫外線誘発アポトーシスを抑制することなども解明した。

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「Toyama Science GALA 2016」において,吉久陽子特命助教が一般部門で特別賞を受賞しました(2016年9月30日)。
演題 “表皮細胞においてmacrophage migration inhibitory factor(MIF)が温熱誘導アポトーシスを抑制する機序の解明”

Free Radical Research誌
吉久陽子特命助教が優れた漢方研究の論文を発表したとして、東海皮膚科漢方研究会から安江賞を受賞しました。

 

 

SFRRI2014
Mati Ur Rehman大学院生が17th Biennial Meeting of Society for Free Radical Research International(SFRRI2014)において「SFRRI2014 Young Investigator Award」を受賞しました。

 

 

Clinical and Experrimental Dermatology誌
竹上與志昌助教の論文の図がClinical and Experrimental Dermatology誌の表紙に紹介されました。(2013)

 

 

Free Radical Research誌
三澤恵診療講師がESDR POSTER PRIZE 2012を受賞しました。The 42nd Annual European Society for Dermatological Research Meeting. September 19-22, 2012. Venice, Italy
Free Radical Research誌
吉久陽子研究員の論文の図がFree Radical Research誌の表紙に紹介されました。(2011)

 

研究業績(英文のみ記載)|富山大学大学院医学薬学研究部皮膚科学講座
研究業績(2005,2006,2007,2008,2009)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2011)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2012)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2013)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2014)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2015)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(20165)|富山大学大学院医学薬学研究部皮膚科学講座 研究業績(2010以前)|富山大学大学院医学薬学研究部皮膚科学講座 adobe readerダウンロード

2017年

Furukawa F, Mizawa M, Makino T, Torai R, Shimizu T.:Efficacy of new low-dose oral anticoagulants in recalcitrant livedoid vasculopathy.

BMJ Case Rep 2017. Jul 24;2017.

Watanabe S, Ohnishi T, Yuasa A, Kiyota H, Iwata S, Kaku M, Watanabe A, Sato J, Hanaki H, Manabe M, Suzuki T, Otsuka F, Aihara M, Iozumi K, Tamaki T, Funada Y, Shinozaki M, Kobayashi M, Okuda M, Kikyo G, Kikuchi K, Okada Y, Takeshima M, Kaneko O, Ogawa N, Ito R, Okuyama R, Shimada S, Shimizu T, Hatta N, Manabu M, Tsutsui K, Tanaka T, Miyachi Y, Asada H, Furukawa F, Kurokawa I, Iwatsuki K, Hide M, Muto M, Yamamoto O, Niihara H, Takagaki K, Kubota Y, Sayama K, Sano S, Furue M, Kanekura T.: The first nationwide surveillance of antibacterial susceptibility patterns of pathogens isolated from skin and soft-tissue infections in dermatology departments in Japan.

J Infect Chemother. 23:503-511.2017.

Makino T, Yoshihisa Y, Mizawa M, Tsutsui K, Nishijima C, Inaoki M, Shimizu T.: Increased serum levels of Th2-type cytokines and eotaxin in fibrillar-type dermatitis herpetiformis.

Acta Derm Venereol. 97(5):642-643, 2017.

Andoh T, Shimizu T.: Increase in sensory sensitivity around, but not in the central part of, the hyperkeratotic papule in lichen amyloidosis.

Br J Dermatol. 177:e143-4,2017.

Makino T, Hara H, Mizawa M, Shimizu A, Kaira K, Shimizu T.: Detection of human papillomavirus type 35 in recurrent Bowen's disease lesions of the fingers.

Eur J Dermatol.,27:198-200, 2017.

Makino T, Ishida W, Hamashima T, Mizawa M, Sasahara M, Shimizu T.: An intermediate vascular tumour between kaposiform hemangioendothelioma and tufted angioma with regression of the skin lesion.

Eur J Dermatol., Apr 1;27(2):175-176, 2017.

Mizawa M, Makino T, Furukawa F, Torai R, Nakano H, Sawamura D, Shimizu T.: The 6-year follow-up of a Japanese patient with silent erythropoietic protoporphyria.

JAAD Case Rep., 3:169-171, 2017.

2016年

Yoshihisa Y, Rehman MU, Kondo T, Shimizu T.: Role of macrophage migration inhibitory factor in heat-induced apoptosis in keratinocytes.

FASEB J., 30:3870-3877, 2016.

Sugita Y, Makino T, Mizawa M, Shimizu T.: Mugwort-mustard allergy syndrome due to broccoli consumption.

Case Rep Dermatol Med., 2016:8413767, 2016.

Rehman MU, Jawaid P, Zhao QL, Li P, Narita K, Katoh T, Shimizu T, Kondo T.:Low-dose spiruchostatin-B, a potent histone deacetylase inhibitor enhances radiation-induced apoptosis in human lymphoma U937 cells via modulation of redox signaling.

Free Radic Res.,50:596-610, 2016.

Jawaid P, Rehman MU, Zhao QL, Takeda K, Ishikawa K, Hori M, Shimizu T, Kondo T.: Helium-based cold atmospheric plasma-induced reactive oxygen species-mediated apoptotic pathway attenuated by platinum nanoparticles.

J Cell Mol Med., 20(9):1737-48,2016.

Winge MC, Ohyama B, Dey CN, Boxer LM, Li W, Ehsani-Chimeh N, Truong AK, Wu D, Armstrong AW, Makino T, Davidson M, Starcevic D, Kislat A, Nguyen NT, Hashimoto T, Homey B, Khavari PA, Bradley M, Waterman EA, Marinkovich MP.: RAC1 activation drives pathologic interactions between the epidermis and immune cells.

J Clin Invest., 2016 Jul 1;126(7):2661-77.

Mizawa M, Makino T, Inami C, Shimizu T.: Jumi-haidoku-to (Shi-Wei-Ba-Du-Tang), a Kampo Formula, ecreases the disease activity of palmoplantar pustulosis.

Dermatol Res Pract., 2016: 4060673,2016.

Makino T, Mizawa M, Seki Y, Hayashi M, Shimizu T.: Decreased filaggrin-2 expression in the epidermis in a case of pityriasis rotunda.
Clin Exp Dermatol., 41:215-217,2016.

Mizawa M, Makino T, Nakano H, Sawamura D, Shimizu T.: Incomplete erythropoietic protoporphyria caused by a splice site modulator homozygous IVS3-48C polymorphism in the ferrochelatase gene.
Br J Dermatol., 174:172-175, 2016.

Jawaid P, Rehman MU, Hassan MH, Zhao QL, Li P, Miyamoto Y, Misawa M, Ogawa R, Shimizu T, Kondo T.: Effect of Platinum Nanoparticles on Cell Death Induced. Ultrasound in Human Lymphoma U937 Cells.

Ultrason Sonochem., 31,206-215, 2016.

Makino T, Shimizu T.; The expression profile of filaggrin-2 in the normal and pathologic human oral mucosa.
Arch Dermatol Res., 308(3):213-7, 2016.

Makino T, Hara H, Hamashima T, Mizawa M, Seki Y, Hayashi H, Shimizu T.; Hodgkin lymphoma presenting as subcutaneous masses in the left upper arm.

J Dermatol., 43:1244-1246, 2016.

Yoshihisa Y, Andoh T, Matsunaga K, Shimizu T.; Efficacy of the astaxanthin for the treatment in a murine model of atopic dermatitis.

PLos One. 29;11(3):e0152288, 2016.

Hara H, Makino T, Shimizu T.: Annular pustular psoriasis associated with colon cancer.

Eur J Dermatol., 1;26(1):104-5, 2016.

Makino T, Shimizu K, Mizawa M, Nakano H, Sawamura D, Shimizu T.: A novel deletion mutation of the ATP2C1 gene in a family with Hailey-Hailey disease.

Eur J Dermatol., 26:414-416,2016.

2015年

Mizawa M, Makino T, Nakamura T, Yamaguchi S, Taki H, Shimizu T.: Exacerbation of symptoms in Blau syndrome/early-onset sarcoidosis following delivery.

Eur J Dermatol., 25:620-622,2015.

Kagoyama K, Makino T, Ueda C, Takegami Y, Shimizu T.: Detection of cytomegalovirus in the gastric ulcer of a patient with drug-induced hypersensitivity syndrome.

J Am Acad Derm Case Report., 215-218, 2015.

Yoshihisa Y, Rehman MU, Yamakoshi-Shibutani T, Shimizu T.: In vitro effects of zinc on the cytokine production from peripheral blood mononuclear cells in patients with zinc allergy.

SpringerPlus., 4:404,2015.

Shimizu K, Andoh T, Yoshihisa Y, Shimizu T.: Histamine released from epidermal keratinocytes plays a role in α-melanocyte-stimulating hormone-induced itching in mice.

Am J Pathol., 185:3003-3010,2015.

Makino T, Mizawa M, Seki Y, Hayashi M, Shimizu T.: Decreased filaggrin-2 expression in the epidermis in a case of pityriasis rotunda.

Clin Exp Dermatol., 25:619-620,2015.

Mori N, Makino T, Mizawa M, Kagoyama K, Kanegane H, Sakaguchi H, Miyazono T, Shimizu T.: Late presentation of X-linked dyskeratosis congenita with a missense mutation in codon 350 of the dyskerin protein.

Eur J Dermatol., 25:75-76, 2015.

Matsui K, Makino T, Mizawa M,Hamashima T, Hanakawa H, Hatta N, Sasahara M, Shimizu T.: Extramammary Paget’s disease arising from Cowden syndrome.

Eur J Dermatol. , 25:89-91, 2015.

Nagata Y, Yoshihisa Y, Rehman MU, Matsunaga K, Kitaichi N, Shimizu T.: Role of macrophage migration inhibitory factor (MIF) in pollen-induced allergic conjunctivitis and pollen dermatitis in mice.

PLoS One 10:e0115593, 2015.

2014年

Makino T, Mori N, Sugiyama H, Mizawa M, Seki Y, Kagoyama K, Shimizu T.: Creeping eruption due to a larva of Spirurina type X.

Lancet. 384:2082, 2014.

Yasuda C, Enomoto E, Ishiwatari S, Mori N, Kagoyama K, Matsunaga K, Yoshihisa Y, Matsukuma S, Shimizu T.: Macrophage migration inhibitory factor (MIF) in the stratum corneum: A marker of the local severity of atopic dermatitis.
Exp Dermatol. 23:764-766, 2014.

Rehman MU, Jawaid P, Yoshihisa Y, Li P, Zhao QL, Narita K, Katoh T, Kondo T, Shimizu T.: Spiruchostatin A and B, novel histone deacetylase inhibitors, induce apoptosis through reactive oxygen species-mitochondria pathway in human lymphoma U937 Cells.
Chemico-Biological Interactions., 221:24-34, 2014.

Makino T, Mizawa M, Yamakoshi T, Takaishi M, Shimizu T.: Expression of filaggrin-2 protein in the epidermis of human skin diseases: A comparative analysis with filaggrin.

Biochem Biophys Res Commun., 449: 100-106, 2014.

Ishida H, Yasue Y, Hachiga T, Andoh T, Akiguchi S, Kuraishi Y, Shimizu T.: Power spectrum and blood flow velocity images obtained by dual-beam backscatter laser Doppler velocimetry.
Opt Rev., 21: 461-467, 2014.

Seki Y, Makino T, Mizawa M, Hamashima T, Sasahara M, Shimizu T.: Immunohistological examination of hand, foot and mouth disease caused by coxsackievirus A6.
Eur J Dermatol., 24:506-507, 2014.

Yamamoto-Tanaka M, Makino T, Motoyama A, Miyai M, Tsuboi R, Hibino T.: Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
Cell Death Dis., 5:e1181, 2014.

Shinoda K, Hayashi R, Taki H, Hounoki H, Makino T, Nomoto K, Shimizu T, Tobe K.: Pseudo-Behcet's disease associated with tuberculosis: a case report and review of the literature.
Rheumatol Int., 34:1471-1474, 2014.

Jawaid P, Rehman UM,Yoshihisa Y, Li P, Zhao QL, Hassan MA, Miyamoto Y, Shimizu T, Kondo T.: Effects of SOD/catalase mimetic platinum nanoparticles on radiation-induced apoptosis in human lymphoma U937 cells.
Apoptosis., 19:1006-1016, 2014.

Hara H, Makino T, Matsui K, Takegami Y, Koga H, Fukuda S, Ishii N, Hashimoto T, Shimizu T: Unusual bullous pemphigoid without infiltration of inflammatory cells in the skin lesions.
Eur J Dermatol., 24:488-489, 2014.

Mizawa M, Makino T, Norisugi O, Hara H, Shimizu K,Nomura K, Kanegane H, Nojima T, Shimizu T.: Primary cutaneous Ewing sarcoma following metastases of bone and lymph nodes.
Br J Dermatol., 171:660-662, 2014.

Yoshihisa Y, Norisugi O, Matsunaga K, Nishihira J, Shimizu T.:Involvement of MIF in Basement Membrane Damage in Chronically UVB- Exposed Skin in Mice.
PLoS One 9: e89569, 2014.

Yoshihisa Y, Rehman MU, Shimizu T.:Astaxanthin, a xanthophyll carotenoid, inhibits ultraviolet-induced apoptosis in keratinocytes. 
Exp Dermatol., 23:178-183, 2014.

Mori N, Mizawa M, Hara H, Norisugi O, Nakano H, Sawamura D, Shimizu T.: Hailey-Hailey disease diagnosed by exacerbation of contact dermatitis with topical crotamiton.

Eur J Dermatol., 24: 263-264, 2014.

Matsui K, Makino T, Takegami Y, Murayama S, Seki Y, Ishii N, Hashimoto T, Shimizu T. :Bullous pemphigoid with IgG anti-LAD-1 antibodies.

Eur J Dermatol., 24:275-276, 2014.

Inoue R, Yoshihisa Y, Tojo Y, Okamura C, Yoshida Y, Kishimoto J, Luan X, Watanabe M, Mizuguchi M, Nabeshima Y, Hamase K, Matsunaga K, Shimizu T, Mori H.: Localization of serine racemase and its role in the skin.

J Invest Dermatol., 134: 1618-1626, 2014.

Mori N, Makino T, Matsui K, Takegami Y Murayama S, Shimizu T.: Successful treatment with UVA rush hardening in a case of solar urticarial.

Eur J Dermatol., 24:117-119, 2014.

Makino T, Seki Y, Hara H, Mizawa M, Matsui K, Shimizu K, Shimizu T.: Induction of skin lesions by ultraviolet B irradiation in a case of pemphigus erythematosus.

Acta Derma Venereol., 94:487-488, 2014.

Norisugi O, Yamakoshi T, Shimizu T.: Successful treatment of lichen amyloidisis using CO2 surgical laser.
Dermatol Ther., 27:71-73, 2014.

Makino T, Yamakoshi T, Mizawa M, Shimizu T.: Ultraviolet B irradiation induces the expression of hornerin in xenotransplanted human skin.
Acta Histochem., 116:20-24, 2014.

Norisugi O, Yoshihisa Y, Shimizu K, Shimizu T.: In vitro cytokine expression by PBMCs in herbal drug-induced skin eruption.
Acta Derma Venereol., 94:58-62, 2014.

2013年

Shimizu K, Makino T, Ueda C, Takegami Y, Matsui K, Mizawa M, Shimizu T.: Detection of hypohidrosis in Japanese patients with pigmentary mosaicism.

Eur J Dermatol., 23:913-914, 2013.

Shimizu T.: Efficacy of Kampo medicine in treating atopic dermatitis: an overview.

Evid Based Complement Alternat Med 2013, 260235, 2013.

Yoshihisa Y, Shimizu T.: HSP70 inducers protect against ultraviolet-induced apoptosis in keratinocytes. “Cellular Response to Physical and Chemical Stress and Therapeutic Applications” edited by Tadamichi Shimizu and Takashi Kondo, 83-99,

Nova Science Publishers, Inc, New York. 2013.

Mizawa M, Yamaguchi M, Ueda C, Makino T, Shimizu T.:Stress evaluation in adult patients with atopic dermatitis using salivary cortisol.
Biomed Res Int., 2013, 138027, 2013.

Ueda C, Makino T, Mizawa M, Norisugi O, Shimizu T.:Granulomatosis with polyangiitis of the skin induced by a chest drainage tube.

Eur J Dermatol. 23:565-567, 2013.

Seki Y, Makino T, Ueda C, Takegami Y, Matsui K, Shimizu T.: Successful treatment with PUVA in a Japanese patient with photosensitive mycosis fungoides: Case report and review of the literatures.
Eur J Dermatol., 23:559-560, 2013.

Ueda C, Makino T, Mizawa M, Shimizu T.: Erythema papulatum centrifugum: A sweat-related dermatitis.

J Am Acad Dermatol., 69: e103-105, 2013.

Yamakoshi T, Andoh T, Makino T, Kuraishi Y, Shimizu T.: Clinical and histopathological features of itch in patients with alopecia areata patients.

Acta Derma Venereol., 93: 575-576, 2013.

Akiguchi S, Ishida H, Andoh T, Shimizu T, Kuraishi Y, Yasuda Y, Hachiga T.: Application of a Micro Multipoint Laser Doppler Velocimeter for in vivo evaluation of subcutaneous blood flow.

IEEJ Trans 8:652-653, 2013.

Murayama S, Mizawa M, Takegami Y, Makino T, Shimizu T.: Two cases of keratosis follicularis squamosa (Dohi) caused by swimsuit friction.

Eur J Dermatol., 23:230-232, 2013.

Yamakoshi T, Makino T, Ur Rheman M, Yoshihisa Y, Sugimori M, Shimizu T.: Trichohyalin-like 1 protein, a member of fused S100 proteins, is expressed in normal and pathologic human skin.

Biochem Biophys Res Commun., 432: 66-72, 2013.

Makino T, Yanagihara M, Oiso N, Furuichi M, Shimizu T.: Repigmentation of the epidermis around the acrosyringium in piebald skin: An ultrastructural examination.
Br J Dermatol., 168: 910-912, 2013. 

Makino T.: Multiple Cutaneous and Uterine Leiomyomatosis. Chapter 13 “Current Genetics in Dermatology” edited by Naoki Oiso, 143-154,

InTech Publisher, Rijeka, 2013.

Takegami Y, Makino T, Matsui K, Ueda C, Fukuda S, Hashimoto T, Shimizu T.: Coexistence of antilaminin-332-type mucous membrane pemphigoid, lamina lucida-type linear IgA bullous dermatosis and Sjogren syndrome.

Clin Exp Dermatol., 38:194-196, 2013.

Yoshihisa Y, Shimizu T.: Platinum nanoparticle and inflammation. “Platinum: Compounds, Production and Applications” edited by Leonid Varennikov and Eduard Yedemsky, 114-122,

Nova Science Publishers, Inc, New York, 2013.

2012年

Mizawa M, Makino T, Hikiami T, Shimada Y, Shimizu T.: Effectiveness of keishibukuryogan on chronic-stage lichenification associated with atopic dermatitis.
ISRN Dermatol., 2012: 158598, 2012.

Yoshihisa Y, Hassan MA, Furusawa Y, Tabuchi Y, Kondo T, Shimizu T.: Alkannin, HSP70 inducer, protects against UVB-induced apoptosis in human keratinocytes.

PLoS One. 7: e47903, 2012.

Makino T, Takegami Y, Rehman MU, Ishida W, Yoshihisa Y, Toyomoto T, Shimizu T.: Maintenance of remission with low dose olopatadine hydrochloride for itch in well-controlled chronic urticaria.

Clin Cosmet Investig Dermatol., 5: 141-146, 2012.

Andoh T, Takayama Y, Yamakoshi T, Lee JB, Sano A, Shimizu T, Kuraishi Y.: Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice.

J Pharmacol Exp Ther. 343:91-6, 2012.

Yoshihisa Y, Shimizu T.: Metal allergy and systemic contact dermatitis: an overview.
Dermatol Res Pract. 2012, 749561, 2012.
Akiguchi S, Ishida H, Andoh T, Hachiga T, Shimizu T, Kuraishi Y, Shirakawa H, Ueyama K.: Measurement of blood flow velocity in a model of stenosis in vitro and in mesenteric vessels in vivo using non-invasive micro multipoint laser Doppler velocimetry.
Meas Sci Technol., 23: 045702, 2012.
Rehman UM, Yoshihisa Y, Miyamoto Y, Shimizu T.: The anti-inflammatory effects of platinum nanoparticles on the LPS-induced inflammatory response in macrophages.
Inflamm Res., 61:1177-1185, 2012.
Yamakoshi T, Makino T, Matsunaga K, Rehman MU, Yoshihisa Y, Seki D, Hayashi Y, Shimizu T.: Efficacy of chlorhexidine gluconate ointment (Oronine H ®) for experimentally-induced comedones.
Clinical Cosmetic Invest Dermatol., 5:79-83, 2012.
Shimizu T.: Macrophage migration inhibitory factor; a mediator of matrix metalloproteinases production. Chapter "Matrix Metalloproteinases: Biology, Functions and Clinical Implications", edited by Namae Oshiro & Eiko Miyagi, pp189-201, Text book of NY Nova Science Publishers, Inc, New York, 2012.
Furuichi M, Makino T, Yamakoshi T, Matsui K, Shimizu T.: Blaschkoid distribution of cylindromas in a germline CYLD mutation carrier.
Br J Dermatol. 166:1376-1378, 2012.
Ishida H, Andoh T, Akiguchi S, Hachiga T, Ishizuka M, Shimizu T, Shirakawa H, Kuraishi Y.: Noninvasive in-vivo measurements of microvessels by reflection-type micro multipoint laser doppler velocimeter.
Jpn J Appl Phys. 51: 032701, 2012.

Fujita Y, Inokuma D, Abe R, Sasaki M, Nakamura H, Shimizu T, Shimizu H.:
Conversion from human haematopoietic stem cells to keratinocytes requires keratinocyte secretory factors.
Clin Exp Dermatol. 37:658-664, 2012.

Yamaguchi M, Date A, Sasaki M, Makino T, Shimizu T.: Rapid and noninvasive biosensor of cathepsin L in the stratum corneum.

Skin Res Technol. 18:332-338, 2012. 

Makino T, Furuichi M, Asano Y, Shimizu T.: A novel mutation of the KRT 10 gene in a Japanese patient with epidermolytic ichthyosis.

J Dermatol., 39: 87-89, 2012.

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Br J Dermatol., 166: 227-229, 2012.

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