Wakana Ohashi, Ph.D.

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Wakana Ohashi, Ph.D
University of Toyama



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Assistant Professor

Academic Background

Reserch Experience

Memberships

 
 
 
 
 
 
 
 
 
 

Biography


Publications

Review

  1. “Control of Macrophage Dynamics as a Potential Therapeutic Approach for Clinical Disorders Involving Chronic Inflammation”
    Ohashi W., Hattori K., Hattori Y.
    J. Pharmacol. Exp. Ther. 354(3), 240-250 (2015)

Original Articles

  1. “Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery.”
    Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y.
    J. Biol. Chem. 276(8), 5836-5840 (2001)
  2. “Stearylated arginine-rich peptides: a new class of transfection systems.”
    Futaki S, Ohashi W, Suzuki T, Niwa M, Tanaka S, Ueda K, Harashima H, Sugiura Y.
    Bioconjug. Chem. 12(6), 1005-1011 (2001)
  3. “Topological stability and self-association of a completely hydrophobic model transmembrane helix in lipid bilayers.”
    Yano Y, Takemoto T, kobayashi S, Yasui H, Sakurai H, Ohashi W, Niwa M, Futaki S, Sugiura Y, Matsuzaki K.
    Biochemistry 41(9), 3073-3080 (2002)
  4. “Backbone 1H, 13C and 15N resonance assignments for the Mg2+-bound form of the Ca2+-binding photoprotein aequorin.”
    Ohashi W, Inouye S, Yamazaki T, Doi-Katayama Y, Yokoyama S, Hirota H.
    J. Biomol. NMR 31(4), 375-376 (2005)
  5. “NMR analysis of the Mg2+-binding properties of aequorin, a Ca2+-binding photoprotein.”
    Ohashi W, Inouye S, Yamazaki T, Hirota H.
    J. Biochem. (Tokyo) 138(6), 613-620 (2005)
  6. “Zinc suppresses Tn17 development via inhibition of STAT3 activation.”
    Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, Ueda N, Azum I, Hirota H, Murakami M, Hirano T.
    Int. Immunol. 22(5), 375-386 (2010)
  7. “Solution structure and fluctuation of the Mg2+-bound form of calmodulin C-terminal domain.”
    Ohashi W, Hirota H, Yamazaki T.
    Protein Sci. 20(4), 690-701 (2011)
  8. “The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth.”
    Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH, Koseki H, Hirano T.
    PLoS One 6(3), e18059 (2011)
  9. “Biochemical characterization of human ZIP13 protein: a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome.”
    Bin BH, Fukada T, Hosaka T, Yamasaki S, Ohashi W, Hojyo S, Miyai T, Nishida K, Yokoyama S, Hirano T.
    J. Biol. Chem. 286(46), 40255-40265 (2011)
  10. “Identification of amino acid residues essential for onion lachrymatory factor synthase activity.”
    Masanura N, Ohashi W, Tsuge N, Imai S, Ishii-Nakamura A, Hirota H, Nagata T, Kumagai H.
    Biosci. Biotechnol. Biochem. 76(3), 447-453 (2012)
  11. “A novel role of the L-type calcium channel a1D subunit as a gatekeeper for intracellular zinc signaling: Zinc wave.”
    Yamasaki S, Hasegawa A, Hojyo S, Ohashi W, Fukada T, Nishida K, Hirano T.
    PLoS One 7(6), e39654 (2012)
  12. “Tonic inhibition by G protein-coupled receptor kinase 2 of Akt/endothelial nitric-oxide syntehase signaling in human vascular endothelial cells under conditions of hyper glycemia with high insulin levels.”
    Taguchi K, Sakata K, Ohashi W, Imaizumi T, Imura J, Hattori Y.
    J. Parmacol. Exp. Ther. 349(2), 199-208 (2014)
  13. “Molecular pathogenesis of Spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutation of ZIP13 proteins”
    Bin BH, Hojyo S, Hosaka T, Bhin J, Kano H, Miyai T, Ikeda M, Kimura-Someya T, Shirouzu M, Cho EG, Fukue K, Kambe T, Ohashi W, Kim KH, Seo J, Choi DH, Nam YJ, Hwang D, Fukunaka A, Fujitani Y, Yokoyama S, Superti-Furga A, Ikegawa S, Lee TR, Fukada T.
    EMBO Mol. Med. 6(8), 1028-1042 (2014)
  14. “Cardiac fibroblasts: contributory role in septic cardiac dysfunction”
    Tomita K, Takashina M, Mizuno N, Sakata K, Hattori K, Imura J, Ohashi W, Hattori Y.
    Journal of Surgical Research 193(2), 874-887 (2014)
  15. “In vivo depletion of CD206+ M2 macrophages exaggerates lung injury in endotoxemic mice”
    Kambara K, Ohashi W, Tomita K, Takashina M, Fujisaka S, Hayashi R, Mori H, Tobe K, Hattori Y.
    The American Journal of Pathology 185(1), 162-171 (2015)
  16. “Anti-inflammatory profile of levosimendan in cecal ligation-induced septic mice and in lipopolysaccharide-stimulated macrophage.” Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abdelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y. Crit. Care Med. 43(11):e508-520 (2015)

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