Tokiko Sizuki, Ph.D.

suzuki

Wakana Ohashi, Ph.D.
University of Toyama



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Assistant Professor

Academic Background

Reserch Experience

Memberships

 
 
 
 
 
 
 
 
 
 

Biography


Publications

Reviews

  1. “Structure-function relationships of EcDOS, a heme-regulated phosphodiesterase from Escherichia coli.”
    Sasakura Y, Yoshimura-Suzuki T, Kurokawa H, Shimizu T. Acc. Chem. Res. 39, 37-43 (2006)
  2. “Dimerization of G protein-coupled purinergic receptors: increasing the diversity of purinergic receptor signal responses and receptor functions.”
    Nakata H, Suzuki T, Namba K, Oyanagi K. J. Recept. Sig. Transd. 30, 337–346 (2010)
  3. “Biochemical assay of G protein-coupled receptor oligomerization: adenosine A1 and thromboxane A2 receptors form the novel functional hetero-oligomer.”
    Mizuno N, Suzuki T, Kishimoto Y, Hirasawa N. Methods Cell Biol. 117, 213-27 (2013)
  4. “Hetero-oligomerization and specificity changes of G protein-coupled purinergic receptors: novel insight into diversification of signal transduction.”
    Suzuki T, Namba K, Mizuno N, Nakata H. Methods Enzymol. 521, 239-257 (2013)

Original Articles

  1. “Relationships between Heme Incorporation, Tetramer Formation, and Catalysis of a Heme-regulated Phosphodiesterase from Escherichia coli: A Study of Deletion and Site-directed Mutants”
    Yoshimura T, Sagami I, Sasakura Y, Shimizu T. J. Biol. Chem. 278, 53105-53111 (2003)
  2. “Characterization of Met95 Mutants of a Heme-regulated Phosphodiesterase from Escherichia coli: Optical Absorption, Magnetic Circular Dichroism, Circular Dichroism, and Redox Potentials”
    Hirata S, Matsui T, Sasakura Y, Sugiyama S, Yoshimura T, Sagami I, Shimizu T. Eur. J. Biochem. 270, 4771-4779 (2003)
  3. “Protein Microarray System for Detecting Protein-Protein Interactions Using an Anti-His-tag Antibody and Fluorescence Scanning: Effects of the Heme Redox State on Protein-Protein Interactions of Heme-regulated Phosphodiesterase from Escherichia coli”
    Sasakura Y, Kanda K, Yoshimura-Suzuki T, Matsui T, Fukuzono S, Han MH, Shimizu T. Anal. Chem. 76, 6521-6527 (2004)
  4. “Critical Roles of Asp40 at the Heme Proximal Side of Heme-regulated Phosphodiesterase from Escherichia coli in Redox Potential, Autooxidation and Catalytic Control”
    Watanabe M, Kurokawa H, Yoshimura-Suzuki T, Sagami I, Shimizu T. Eur. J. Biochem. 271, 3937-3942 (2004)
  5. “DOSEc, a Heme-Regulated Phosphodiesterase, Plays an Important Role in the Regulation of the Cyclic AMP Level in Escherichia coli”
    Yoshimura-Suzuki T, Sagami I, Yokota N, Kurokawa H, Shimizu T. J. Bacteriol.187, 6678-6682 (2005)
  6. “Investigation of the relationship between protein-protein interaction and catalytic activity of a heme-regulated phosphodiesterase from Escherichia coli (Ec DOS) by protein microarray.”
    Sasakura Y, Kanda K, Yoshimura-Suzuki T, Matsui T, Fukuzono S, Shimizu T. Biochem. 44, 9598-9605 (2005)
  7. “Regulation of pharmacology by hetero-oligomerization between A1 adenosine receptor and P2Y2 receptor.”
    Suzuki T, Namba K, Tsuga H, Nakata H. Biochem. Biophys. Res. Commun. 351, 559-565 (2006)
  8. “A highly conserved tryptophan residue in the fourth transmembrane domain of the A1 adenosine receptor is essential for ligand binding but not receptor homodimerization”
    Suzuki T, Namba K, Yamagishi R, Kaneko H, Haga T, Nakata H. J. Neurochem. 110, 1352-1362 (2009)
  9. “Immunogold electron microscopic evidence of in situ formation of homo- and heteromeric purinergic adenosine A1 and P2Y2 receptors in rat brain”
    Namba K, Suzuki T, Nakata H. BMC Res. Not. 3, 323 (2010)
  10. “Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function”
    Suzuki T, Obara Y, Moriya T, Nakata H, Nakahata N. FEBS lett. 585, 3978-3984 (2011)
  11. “Hetero-oligomerization between adenosine A₁ and thromboxane A₂ receptors and cellular signal transduction on stimulation with high and low concentrations of agonists for both receptors.”
    Mizuno N, Suzuki T, Hirasawa N, Nakahata N. Eur. J. Pharmacol. 677, 5-14 (2012)

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