154. Nawaz A, Bilal M, Fujisaka S, Kado T, Aslam MR, Ahmed S, Okabe K, Igarashi Y, Watanabe Y, Kuwano T, Tsuneyama K, Nishimura A, Nishida Y, Yamamoto S, Sasahara M, Imura J, Mori H, Matzuk MM, Kudo F, Manabe I, Uezumi A, Nakagawa T, Oishi Y, Tobe K. Depletion of CD206⁺ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration. Nat Commun.13(1): 7058. 2022.

153. Yamamoto S, Yamamoto S, Akai T, Sasahara M, Kuroda S. Differentiation of Fibroblasts Into Myofibroblasts in the Arachnoid Membrane of Moyamoya Disease.Stroke. 53(11): 3465-73. 2022.

152. Tsuneki H, Maeda T, Takata S, Sugiyama M, Otsuka K, Ishizuka H, Onogi Y, Tokai E, Koshida C, Kon K, Takasaki I, Hamashima T, Sasahara M, Rudich A, Koya D, Sakurai T, Yanagisawa M, Yamanaka A, Wada T, Sasaoka T.Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity.Cell Rep. 41(3): 111497. 2022.

151. Sakai A, Igarashi T, Yoshioka I, Shibuya K, Kimura N, Tohmatsu Y, Watanabe T, Hirano K, Tanaka H, Onoda S, Okuno N, Hamashima T, Imura J, Satake T, Fujii T. A 47-Year-Old Man with Advanced Distal Pancreatic Carcinoma and an Initial Partial Response to Chemotherapy Requiring Celiac Axis Reconstruction of the Common Hepatic Artery and Left Gastric Artery. Am J Case Rep.23: e936840. 2022.

150. Akai T, Hatta T, Sakata-Haga H, Yamamoto S, Otani H, Yamamoto S, Kuroda S. Cerebrospinal fluid may flow out from the brain through the frontal skull base and choroid plexus: a gold colloid and cadaverine injection study in mouse fetus. Childs Nerv Syst. 37(10): 3013-20. 2021.

149. Tanaka T, Wada T, Uno K, Ogihara S, Ie H, Okekawa A, Ishikawa A, Ito T, Miyazawa Y, Sameshima A, Onogi Y, Tsuneki H, Sasahara M, Nakashima A, Saito S, Sasaoka T. Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus. Diabetologia. 64: 1660-73. 2021.

148. Nakamura T, Kurosaki K, Kanemoto M, Sasahara M, Ichijo H. Early-life experiences altered the maturation of the lateral habenula in mouse models, resulting in behavioural disorders in adulthood. J Psychiatry Neurosci. 46: E480-9. 2021.

147. Kuwano T, Izumi H, Aslam MR, Igarashi Y, Bilal M, Nishimura A, Watanabe Y, Nawaz A, Kado T, Ikuta K, Yamamoto S, Sasahara M, Fujisaka S, Yagi K, Mori H, Tobe K. Generation and characterization of a Meflin-CreER^T2 transgenic line for lineage tracing in white adipose tissue. PLoS One. 16: e0248267. 2021.

146. Yoshida N, Yamamoto S, Hamashima T, Okuno N, Okita N, Horikawa S, Hayashi M, Dang TC, Nguyen QL, Nishiyama K, Makino T, Ishii Y, Tomihara K, Shimizu T, Shibuya M, Noguchi M, Sasahara M. Dysregulation of Amphiregulin stimulates the pathogenesis of cystic lymphangioma. Proc Natl Acad Sci USA. 118(19): e2019580118. 2021.

145. Morita M, Toida A, Horiuchi Y, Watanabe S, Sasahara M, Kawaguchi K, So T, Imanaka T. Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2K^btsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy. Heliyon. 7(2): e06228. 2021.

144. Nguyen QL, Okuno N, Hamashima T, Dang ST, Fujikawa M, Ishii Y, Enomoto A, Maki T, Nguyen HN, Nguyen VT, Fujimori T, Mori H, Andrae J, Betsholtz C, Takao K, Yamamoto S, Sasahara M. Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice. Angiogenesis. 24(1): 35-46. 2021.

143. Morita M, Kaizawa T, Yoda T, Oyama T, Asakura R, Matsumoto S, Nagai Y, Watanabe Y, Watanabe S, Kobayashi H, Kawaguchi K, Yamamoto S, Shimozawa N, So T, Imanaka T. Bone marrow transplantation into Abcd1-deficient mice: distribution of donor derived-cells and biological characterization of the brain of the recipient mice. J Inherit Metab Dis. 44(3): 718-27. 2021.

142. Makino T, Mizawa M, Yoshihisa Y, Yamamoto S, Tabuchi Y, Miyai M, Hibino T, Sasahara M, Shimizu T. Trichohyalin-like 1 protein plays a crucial role in proliferation and anti-apoptosis of normal human keratinocytes and squamous cell carcinoma cells. Cell Death Discov. 6: 109. 2020.

141. Nishida Y, Nawaz A, Kado T, Takikawa A, Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, Imura J, Tokuyama K, Usui I, Nakagawa T, Fujisaka S, Kunimasa Y, Tobe K. Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway. J Cachexia Sarcopenia Muscle. 11(1): 241-58. 2020.

140. Fujisaka S, Usui I, Nawaz A, Igarashi Y, Okabe K, Furusawa Y, Watanabe S, Yamamoto S, Sasahara M, Watanabe Y, Nagai Y, Yagi K, Nakagawa T, Tobe K. Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity. Sci Rep. 10(1): 5544. 2020.

139. Watanabe E, Wada T, Okekawa A, Kitamura F, Komatsu G, Onogi Y, Yamamoto S, Sasahara M, Kitada M, Koya D, Tsuneki H, Sasaoka T. Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity. Angiogenesis. 23(4): 667-84. 2020.

138. Kanemoto M, Nakamura T, Sasahara M, Ichijo H. Stress-Related Neuronal Clusters in Sublenticular Extended Amygdala of Basal Forebrain Show Individual Differences of Positions. Front Neural Circuits. 14: 29. 2020.

137. Hayashi T, Yamamoto S, Hamashima T, Mori H, Sasahara M, Kuroda S.Critical role of platelet-derived growth factor-α in angiogenesis after indirect bypass in a murine moyamoya disease model. J Neurosurg. 22: 1-9. 2020.

136. Hamashima T, Ishii Y, Nguyen QL, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M. Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 436(1): 11-26. 2020.

135. Hofer DC, Zirkovits G, Pelzmann HJ, Huber K, Pessentheiner AR, Xia W, Uno K, Miyazaki T, Kon K, Tsuneki H, Pendl T, Al Zoughbi W, Madreiter-Sokolowski CT, Trausinger G, Abdellatif M, Schoiswohl G, Schreiber R, Eisenberg T, Magnes C, Sedej S, Eckhardt M, Sasahara M, Sasaoka T, Nitta A, Hoefler G, Graier WF, Kratky D, Auwerx J, Bogner-Strauss JG. N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health. FASEB J. 33(12): 13808-24. 2019.

134. Kon K, Tsuneki H, Ito H, Takemura Y, Sato K, Yamazaki M, Ishii Y, Sasahara M, Rudich A, Maeda T, Wada T, Sasaoka T. Chronotherapeutic effect of orexin antagonists on glucose metabolism in diabetic mice. J Endocrinol. 243(1): 59-72. 2019.

133. Watanabe Y, Nagai Y, Honda H, Okamoto N, Yanagibashi T, Ogasawara M, Yamamoto S, Imamura R, Takasaki I, Hara H, Sasahara M, Arita M, Hida S, Taniguchi S, Suda T, Takatsu K. Bidirectional crosstalk between neutrophils and adipocytes promotes adipose tissue inflammation. FASEB J. 33(11): 11821-35. 2019.

132. Dang TC, Ishii Y, Nguyen V, Yamamoto S, Hamashima T, Okuno N, Nguyen QL, Sang Y, Ohkawa N, Saitoh Y, Shehata M, Takakura N, Fujimori T, Inokuchi K, Mori H, Andrae J, Betsholtz C, Sasahara M. Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain. Cell Rep. 27: 1073-89.e5. 2019.

131. Shen J, Xu G, Zhu R, Yuan J, Ishii Y, Hamashima T, Matsushima T, Yamamoto S, Takatsuru Y, Nabekura J, Sasahara M. PDGFR-b restores blood-brain barrier functions in a mouse model of focal cerebral ischemia. J Cereb Blood Flow Metab. 39(8): 1501-15. 2019.

130. Ozaki H, Inoue R, Matsushima T, Sasahara M, Hayashi A, Mori H. Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy. PLoS One. 13(1): e0190864. 2018.

129. Yamada K, Hamashima T, Ishii Y, Yamamoto S, Okuno N, Yoshida N, Yamada M, Huang TT, Shioda N, Tomihara K, Fujimori T, Mori H, Fukunaga K, Noguchi M, Sasahara M. Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast. Cell Physiol Biochem. 51(3): 1461-79. 2018.

128. Igarashi Y, Nawaz A, Kado T, Bilal M, Kuwano T, Yamamoto S, Sasahara M, Jiuxiang X, Inujima A, Koizumi K, Imura J, Shibahara N, Usui I, Fujisaka S, Tobe K. Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation. Sci Rep.8(1): 14567. 2018.

127. Kitahara H, Kajikawa S, Ishii Y, Yamamoto S, Hamashima T, Azuma E, Sato H, Matsushima T, Shibuya M, Shimada Y, Sasahara M. The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model. EBioMedicine. 31:190-201. 2018.

126. Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y. NK Cells Control Tumor-Promoting Function of Neutrophils in Mice. Cancer Immunol Res. 6(3): 348-57. 2018.

125. Ozaki H, Inoue R, Matsushima T, Sasahara M, Hayashi A, Mori H. Serine racemase deletion attenuates neurodegeneration and microvascular damage in diabetic retinopathy. PLoS One. 13(1): e0190864. 2018.

124. Nawaz A, Mehmood A, Kanatani Y, Kado T, Igarashi Y, Takikawa A, Yamamoto S, Okabe K, Nakagawa T, Yagi K, Fujisaka S, Tobe K. Publisher Correction: Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice. Sci Rep. 8(1): 14597. 2018.

123. Nakaoka H, Hirono K, Yamamoto S, Takasaki I, Takahashi K, Kinoshita K, Takasaki A, Nishida N, Okabe M, Ce W, Miyao N, Saito K, Ibuki K, Ozawa S, Adachi Y, Ichida F. MicroRNA-145-5p and microRNA-320a encapsulated in endothelial microparticles contribute to the progression of vasculitis in acute Kawasaki Disease. Sci Rep. 8(1): 1016. 2018.

122. 森田誠市，尾矢剛志，石井陽子，ヘムラグル・サビット，徳永綾乃，石澤 伸，山本誠士，濱島 丈，倉茂洋一，松島貴子，塚田一博，笹原正清．マウス肝臓星細胞の活性化における血小板由来増殖因子ベータ受容体の役割．(THE ROLE OF PLATELET-DERIVED GROWTH FACTOR RECEPTOR β IN THE ACTIVATION OF MOUSE HEPATIC STELLATE CELLS). Toyama Med J. 27(1): 14-22. 2017.

121. Yamamoto S, Muramatsu M, Azuma E, Ikutani M, Nagai Y, Sagara H, Koo BN, Kita S, O'Donnell E, Osawa T, Takahashi H, Takano K, Dohmoto M, Sugimori M, Usui I, Watanabe Y, Hatakeyama N, Iwamoto T, Komuro I, Takatsu K, Tobe K, Niida S, Matsuda N, Shibuya M, Sasahara M. A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS. Sci Rep. 7(1): 3855. 2017.

120. Wada T, Ishikawa A, Watanabe E, Nakamura Y, Aruga Y, Hasegawa H, Onogi Y, Honda H, Nagai Y, Takatsu K, Ishii Y, Sasahara M, Koya D, Tsuneki H, Sasaoka T. Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance. J Endocrinol. 235(3): 179-191. 2017.

119. Onogi Y, Wada T, Kamiya C, Inata K, Matsuzawa T, Inaba Y, Kimura K, Inoue H, Yamamoto S, Ishii Y, Koya D, Tsuneki H, Sasahara M, Sasaoka T. PDGFRβ Regulates Adipose Tissue Expansion and Glucose Metabolism via Vascular Remodeling in Diet-Induced Obesity. Diabetes. 66(4): 1008-21. 2017.

118. Yokose J, Okubo-Suzuki R, Nomoto M, Ohkawa N, Nishizono H, Suzuki A, Matsuo M, Tsujimura S, Takahashi Y, Nagase M, Watabe AM, Sasahara M, Kato F, Inokuchi K. Overlapping memory trace indispensable for linking, but not recalling, individual memories. Science. 355(6323): 398-403. 2017.

117. Yamazaki T, Nalbandian A, Uchida Y, Li W, Arnold TD, Kubota Y, Yamamoto S, Ema M, Mukouyama Y: Tissue myeloid progenitors differentiate into pericytes through TGF-β signaling in developing skin vasculature. Cell Rep. 18(12): 2991-3004. 2017.

116. Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, Saeki K, Usui I, Fujisaka S, Tobe K. CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. Nat Commun. 8(1): 286. 2017.

115. Shioda N, Yabuki Y, Wang Y, Uchigashima M, Hikida T, Sasaoka T, Mori H, Watanabe M, Sasahara M, Fukunaga K. Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons. Mol Psychiatry. 22(8): 1205-22. 2016.

114. Hori E, Hayakawa Y, Hayashi T, Hori S, Okamoto S, Shibata T, Kubo M, Horie Y, Sasahara M, Kuroda S. Mobilization of Pluripotent Multilineage-Differentiating Stress-Enduring Cells in Ischemic Stroke. J Stroke Cerebrovasc Dis. 25(6): 1473-81. 2016.

113. Kawaguchi M, Hara N, Bilim V, Koike H, Suzuki M, Kim TS, Gao N, Dong Y, Zhang S, Fujinawa Y, Yamamoto O, Ito H, Tomita Y, Naruse Y, Sakamaki A, Ishii Y, Tsuneyama K, Inoue M, Itoh J, Yasuda M, Sakata N, Jung CG, Kanazawa S, Akatsu H, Minato H, Nojima T, Asai K, Miura Y. A diagnostic marker for superficial urothelial bladder carcinoma: lack of nuclear ATBF1 (ZFHX3) by immunohistochemistry suggests malignant progression. BMC Cancer. 16(1): 805. 2016.

112. Saito K, Nakaoka H, Takasaki I, Hirono K, Yamamoto S, Kinoshita K, Miyao N, Ibuki K, Ozawa S, Watanabe K, Bowles NE, Ichida F. MicroRNA-93 may control vascular endothelial growth factor A in circulating peripheral blood mononuclear cells in acute Kawasaki disease. Pediatr Res. 80(3): 425-32. 2016.

111. Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Arif A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K. HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance. Diabetes. 65(12): 3649-59. 2016.

110. Tsuneki H, Kon K, Ito H, Yamazaki M, Takahara S, Toyooka N, Ishii Y, Sasahara M, Wada T, Yanagisawa M, Sakurai T, Sasaoka T. Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice. Endocrinology. 157(11): 4146-57. 2016.

109. Yamamoto S, Azuma E, Muramatsu M, Hamashima T, Ishii Y, Sasahara M. Significance of Extracellular Vesicles: Pathobiological Roles in Disease. Cell Struct Funct. 41(2): 137-143. 2016.

108. Hosaka K, Yang Y, Seki T, Fischer C, Dubey O, Fredlund E, Hartman J, Religa P, Morikawa H, Ishii Y, Sasahara M, Larsson O, Cossu G, Cao R, Lim S, Cao Y. Pericyte-fibroblast transition promotes tumor growth and metastasis. Proc Natl Acad Sci USA. 113(38): E5618-27. 2016.

107. Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake, K, Takatsu K. Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice. Sci Rep. 6: 23097. 2016.

106. Zheng Y, Yamamoto S, Ishii Y, Sang Y, Hamashima T, Van De N, Nishizono H, Inoue R, Mori H, Sasahara M. Glioma-Derived Platelet-Derived Growth Factor-BB Recruits Oligodendrocyte Progenitor Cells via Platelet-Derived Growth Factor Receptor-α and Remodels Cancer Stroma. Am J Pathol. 186(5): 1081-91.2016.

105. Sato H, Ishii Y, Yamamoto S, Azuma E, Takahashi Y, Hamashima T, Umezawa A, Mori H, Kuroda S, Endo S, Sasahara M. PDGFR-β Plays a Key Role in the Ectopic Migration of Neuroblasts in Cerebral Stroke. Stem Cells. 34(3): 685-98. 2016.

104. Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, Shen J, Inoue R, Nishizono H, Itoh H, Majima M, Abraham D, Miyawaki T, Sasahara M. PDGFRα plays a crucial role in connective tissue remodeling. Sci Rep. 5: 17948. 2015.

103. Yamamoto S, Niida S, Azuma E, Yanagibashi T, Muramatsu M, Huang TT, Sagara H, Higaki S, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Hamashima T, Mori H, Matsuda N, Ishii Y, Sasahara M. Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes. Sci Rep. 5: 8505. 2015.

102. Nakamura T, Matsumoto J, Takamura Y, Ishii Y, Sasahara M, Ono T, Nishijo H. Relationships among parvalbumin-immunoreactive neuron density, phase-locked gamma oscillations, and autistic/schizophrenic symptoms in PDGFR-β knock-out and control mice. PLoS One. 10(3): e0119258. 2015.

101. Sameshima A, Wada T, Ito T, Kashimura A, Sawakawa K, Yonezawa R, Tsuneki H, Ishii Y, Sasahara M, Saito S, Sasaoka T. Teneligliptin improves metabolic abnormalities in a mouse model of postmenopausal obesity. J Endocrinol. 227(1): 25-36. 2015.

100. Akao T, Oyanagi Y, Shiotsuki S, Ishii Y, Sasahara M. Metabolism of dextran sulfate sodium by intestinal bacteria in rat cecum is related to induction of colitis. Biol Pharm Bull. 38(4): 566-70. 2015.

99. Sugimori M, Hayakawa Y, Boman BM, Fields JZ, Awaji M, Kozano H, Tamura R, Yamamoto S, Ogata T, Yamada M, Endo S, Kurimoto M, Kuroda S. Discovery of Power-Law Growth in the Self-Renewal of Heterogeneous Glioma Stem Cell Populations. PLoS One. 10(8): e0135760. 2015.

98. Hayashi S, Hamada T, Zaidi SF, Oshiro M, Lee J, Yamamoto T, Ishii Y, Sasahara M, Kadowaki M. Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice. Am J Physiol Gastrointest Liver Physiol. 307(10): G968-78. 2014.

97. Suzuki H, Takasawa S, Usui I, Ishii Y, Kato I, Okamoto H, Kobayashi M, Sasahara M, Tobe K. The Ca2+/calmodulin-dependent protein kinase IIα(Thr286Asp) transgenic mice: a novel mouse model of severe insulin-dependent diabetes. Austin J Endocrinol Diabetes. 1(1): 1002. 2014.

96. Kuroda N, Imamura Y, Hamashima T, Ohe C, Mikami S, Nagashima Y, Inoue K, Perez-Montiel D, Petersson F, Michal M, Hes O. Review of small cell carcinoma of the kidney with focus on clinical and pathobiological aspects. Pol J Pathol. 65(1): 15-9. 2014.

95. Zheng LS, Ishii Y, Zhao QL, Kondo T, Sasahara M. PDGF suppresses oxidative stress induced Ca2+ overload and calpain activation in neurons. Oxid Med Cell Longev. 367206. 2013.

94. Zhao J, Urakawa S, Matsumoto J, Li R, Ishii Y, Sasahara M, Peng Y, Ono T, Nishijo H. Changes in Otx2 and Parvalbumin Immunoreactivity in the Superior Colliculus in the Platelet-Derived Growth Factor Receptor-β Knockout Mice. Biomed Res Int. 848265. 2013.

93. Wada T, Miyashita Y, Sasaki M, Aruga Y, Nakamura Y, Ishii Y, Sasahara M, Kanasaki K, Kitada M, Koya D, Shimano H, Tsuneki H, Sasaoka T. Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. Am J Physiol Endocrinol Metab. 305(11): E1415-25. 2013.

92. Wada T, Onogi Y, Kimura Y, Nakano T, Fusanobori H, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T. Cilostazol ameliorates systemic insulin resistance in diabetic db/db mice by suppressing chronic inflammation in adipose tissue via modulation of both adipocyte and macrophage functions. Eur J Pharmacol. 707(1-3): 120-9. 2013.

91. Ichihara Y, Wada T, Soeda Y, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T. SH2-containing inositol 5'-phosphatase 2 (SHIP2) selectively impaired hypothalamic insulin signalling and regulation of food intake in mice. J Neuroendocrinol. 25(4): 372-82. 2013.

90. Xu G, Shen J, Ishii Y, Fukuchi M, Dang TC, Zheng Y, Hamashima T, Fujimori T, Tsuda M, Funa K, Sasahara M. Functional Analysis of Platelet-Derived Growth Factor Receptor-β in Neural Stem/Progenitor Cells. Neuroscience. 238: 195-208. 2013.

89. Ichikawa T, Hayashi R, Suzuki K, Imanishi S, Kambara K, Okazawa S, Inomata M, Yamada T, Yamazaki Y, Koshimizu Y, Miwa T, Matsui S, Usui I, Urakaze M, Matsuya Y, Sasahara M, Tobe K. Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma. Respirology. 18(2): 332-9. 2013.

88. Yonezawa R, Wada T, Matsumoto N, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Saito S, Sasaoka T. Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet. Am J Physiol Endocrinol Metab. 303(4): E445-56. 2012.

87. Imanishi S, Hayashi R, Ichikawa T, Suzuki K, Sasahara M, Kondo T, Ogawa H, Tobe K. SRT1720, A SIRT1 Activator, Aggravates Bleomycin-Induced Lung Injury in Mice. Food and Nutrition Sciences. 3: 157-63. 2012.

86. Shen J, Ishii Y, Xu G, Dang TC, Hamashima T, Matsushima T, Yamamoto S, Hattori Y, Takatsuru Y, Nabekura J, Sasahara M. PDGFR-β as a positive regulator of tissue repair in a mouse model of focal cerebral ischemia. J Cereb Blood Flow Metab. 32(2): 353-67. 2012.

85. Shioda N, Moriguchi S, Oya T, Ishii Y, Shen J, Matsushima T, Nishijo H, Sasahara M, Fukunaga K. Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice. Hippocampus. 22(6): 1371-8. 2012.

84. Xue Y, Lim S, Yang Y, Wang Z, Jensen LD, Hedlund EM, Andersson P, Sasahara M, Larsson O, Galter D, Cao R, Hosaka K, Cao Y. PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells. Nat Med. 18(1): 100-10. 2011.

83. Suzuki H, Usui I, Kato I, Oya T, Kanatani Y, Yamazaki Y, Fujisaka S, Senda S, Ishii Y, Urakaze M, Mahmood A, Takasawa S, Okamoto H, Kobayashi M, Tobe K, Sasahara M. Deletion of platelet-derived growth factor receptor-β improves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα (Thr286Asp) transgenic mice. Diabetologia. 54(11): 2953-62. 2011.

82. Nakagawa T, Izumino K, Ishii Y, Oya T, Hamashima T, Jie S, Ishizawa S, Tomoda F, Fujimori T, Nabeshima YI, Inoue H, Sasahara M. Roles of PDGF receptor-beta in the structure and function of postnatal kidney glomerulus. Nephrol Dial Transplant. 26(2): 458-68. 2011.

81. Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I. Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice. Hippocampus. 21(6): 678-87. 2011.

80. Hasegawa T, Ishii Y, Yonezawa R, Yoneda N, Shima T, Nakashima A, Hidaka T, Saito S. Stage I ovarian cancer cases during early, mid and late pregnancy periods: Three case reports and review of the literature. J Obstet Gynaecol Res. 37(6): 650-5. 2011.

79. Nguyen PT, Nakamura T, Hori E, Urakawa S, Uwano T, Zhao J, Li R, Bac ND, Hamashima T, Ishii Y, Matsushima T, Ono T, Sasahara M, Nishijo H. Cognitive and socio-emotional deficits in platelet-derived growth factor receptor-β gene knockout mice. PLoS One. 6(3): e18004. 2011.

78. Li Y, Shen J. Recent Developments in Thyroid Cancer Molecular Markers. Chin. J Cancer Prev Treat. 18: 59-62. 2011.

77. Dong XY, Sun X, Guo P, Li Q, Sasahara M, Ishii Y, Dong JT. ATBF1 inhibits estrogen receptor (ER) function by selectively competing with AIB1 for binding to the ER in ER-positive breast cancer cells. J Biol Chem. 285(43): 32801-9. 2010.

76. Wada T, Kenmochi H, Miyashita Y, Sasaki M, Ojima M, Sasahara M, Koya D, Tsuneki H, Sasaoka T. Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. Endocrinology. 151(5): 2040-9. 2010.

75. Zheng L, Ishii Y, Tokunaga A, Hamashima T, Shen J, Zhao QL, Ishizawa S, Fujimori T, Nabeshima Y, Mori H, Kondo T, Sasahara M. Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved. J Neurosci Res. 88(6): 1273-84. 2010.

74. Ohi Y, Ishii Y, Sasahara M, Haji A. Involvement of platelet-derived growth factor-BB and its receptor-β in hypoxia-induced depression of excitatory synaptic transmission in the nucleus tractus solitarius of mice. J Pharmacol Sci. 112(4): 477-81. 2010.

73. Takeuchi K, Yokoyama M, Ishizawa S, Terui Y, Nomura K, Marutsuka K, Nunomura M, Fukushima N, Yagyuu T, Nakamine H, Akiyama F, Hoshi K, Matsue K, Hatake K, Oshimi K. Lymphomatoid gastropathy: a distinct clinicopathologic entity of self-limited pseudomalignant NK-cell proliferation. Blood. 116: 5631-7. 2010.

72. Taki H, Shinoda K, Hounoki H, Ogawa R, Ishizawa S, Sugiyama E, Tobe K. Serum interleukin-5 levels correlate with disease activity of Churg-Strauss syndrome in a patient treated with a leucotriene receptor antagonist, pranlukast, and inhaled corticosteroid. Scand J Rheumatol. 39: 341-3. 2010.

71. Doshi M, Kuwatori Y, Ishii Y, Sasahara M, Hirashima Y. Hypothermia during Ischemia Protects against Neuronal Death but Not Acute Brain Edema following Transient Forebrain Ischemia in Mice. Biol Pharm Bull. 32(12): 1957-61. 2009.

70. Yamazaki T, Hemragul S, Oya T, Ishii Y, Hamashima T, Tokunaga A, Ishizawa S, Shen J, Kurashige Y, Matsushima T, Furuta I, Noguchi M, Sasahara M. Activation of MAP kinases, Akt and PDGF receptors in injured peripheral nerves. J Peripheral Nervous System. 14(3): 165-76. 2009.

69. Nagai S, Kurimoto M, Ishizawa S, Hayashi N, Hamada H, Kamiyama H, Endo S. A rare astrocytic tumor with rhabdoid features. Brain Tumor Pathol. 26: 19-24. 2009.

68. Tsunekawa S, Ohi Y, Ishii Y, Sasahara M, Haji A. Hypoxic ventilatory response in platelet-derived growth factor receptor-beta-knockout mice. J Pharmacol Sci. 110(3): 270-5. 2009.

67. Kudo H, Yata Y, Takahara T, Kawai K, Nakayama Y, Kanayama M, Oya T, Morita S, Sasahara M, Mann DA, Sugiyama T. Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue. Liver Int. 29(7): 988-96. 2009.

66. Suzuki H, Kato I, Usui I, Takasaki I, Tabuchi Y, Oya T, Tsuneyama K, Kawaguchi H, Hiraga K, Takasawa S, Okamoto H, Tobe K, Sasahara M. Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice. Biochem Biophys Res Commun. 379(1): 38-42. 2009.

65. Zen Y, Onodera M, Inoue D, Kitao A, Matsui O, Nohara T, Namiki M, Kasashima S, Kawashima A, Matsumoto Y, Katayanagi K, Murata T, Ishizawa S, Hosaka N, Kuriki K, Nakanuma Y. Retroperitoneal fibrosis: a clinicopathologic study with respect to immunoglobulin G4. Am J Surg Pathol . 33: 1833-9. 2009.

64. Takasawa A, Kato I, Takasawa K, Ishii Y, Yoshida T, Shehata MH, Kawaguchi H, Mohafez OM, Sasahara M, Hiraga K. Mutation-, aging-, and gene dosage-dependent accumulation of neuroserpin (G392E) in endoplasmic reticula and lysosomes of neurons in transgenic mice. J Biol Chem. 283(51): 35606-13. 2008.

63. Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nakada S, Ishii Y, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H, Hiraga K. A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells. Diabetes Metab Res Rev. 24(6): 486-97. 2008.

62. Tokunaga A, Oya T, Ishii Y, Motomura H, Nakamura C, Ishizawa S, Fujimori T, Nabeshima YI, Umezawa A, Kanamori M, Kimura T, Sasahara M. PDGF receptor s is a potent regulator of mesenchymal stromal cell function. J Bone Miner Res. 23(9): 1519-28. 2008.

61. Coston WM, Loera S, Lau SK, Ishizawa S, Jiang Z, Wu CL, Yen Y, Weiss LM, Chu PG. Distinction of Hepatocellular Carcinoma From Benign Hepatic Mimickers Using Glypican-3 and CD34 Immunohistochemistry. Am J Surg Pathol. 32(3): 433-44. 2008.

60. Ishii Y, Matsumoto Y, Watanabe R, Elmi M, Fujimori T, Nissen J, Cao Y, Nabeshima YI, Sasahara M, Funa K. Characterization of neuroprogenitor cells expressing the PDGF beta-receptor within the subventricular zone of postnatal mice. Mol Cell Neurosci. 37(3): 507-18. 2008.

59. Kagawa S, Soeda Y, Ishihara H, Oya T, Sasahara M, Yaguchi S, Oshita R, Wada T, Tsuneki H, Sasaoka T. Impact of transgenic overexpression of SH2-Containing Inositol 5’-Phosphatase 2 on glucose metabolism and insulin signaling in mice. Endocrinology. 149(2): 642-50. 2008.

58. Mio F, Chiba K, Hirose Y, Kawaguchi Y, Mikami Y, Oya T, Mori M, Kamata M, Matsumoto M, Ozaki K, Tanaka T, Takahashi A, Kubo T, Kimura T, Toyama Y, Ikegawa S. A functional polymorphism in COL11A1, which encodes the α1 chain of type XI collagen, is associated with susceptibility to lumbar disc herniation. Am J Hum Genet. 81(6): 1271-7. 2007.

57. Tang J, Akao T, Nakamura N, Wang ZT, Takagawa K, Sasahara M, Hattori M. In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors. Drug Metab Dispos. 35(10): 1832-9. 2007.

56. Ohi Y, Ishii Y, Haji A, Noguchi S, Sasaoka T, Fujimori T, Nabeshima YI,　Sasahara M, Hattori Y. Platelet-derived growth factor (PDGF)-BB inhibits AMPA receptor-mediated synaptic transmission via PDGF receptor-beta in murine nucleus tractus solitarius. Brain Res. 1159: 77-85. 2007.

55. Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K. Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia. Stroke. 38(3): 1063-8. 2007.

54. Yamamoto H, Kohashi K, Oda Y, Tamiya S, Takahashi Y, Kinoshita Y, Ishizawa S, Kubota M, Tsuneyoshi M. Absence of human herpesvirus-8 and Epstein-Barr virus in inflammatory myofibroblastic tumor with anaplastic large cell lymphoma kinase fusion gene. Pathol Int. 56(10): 584-90. 2006.

53. Yamabe N, Yokozawa T, Oya T, Kim M. Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats. J Pharmacol Exp Ther. 319(1): 228-36. 2006.

52. Hemmi K, Ma D, Miura Y, Kawaguchi M, Sasahara M, Hashimoto-Tamaoki T, Tamaoki T, Sakata N, Tsuchiya K. A homeodomain-zinc finger protein, ZFHX4, is expressed in neuronal differentiation manner and suppressed in muscle differentiation manner. Biol Pharm Bull. 29(9): 1830-5. 2006.

51. Cheng C, Tsuneyama K, Zheng H, Oya T, Cui Z, Feril LB Jr, Takano Y. Enhanced scavenging of lipid substances is a possible effect of corticosteroids in the treatment of cholesterol crystal embolism. Pathol Res Pract. 202(8): 591-8. 2006.

50. Ishii Y, Oya T, Zheng L, Gao Z, Kawaguchi M, Sabit H, Matsushima T, Tokunaga A, Ishizawa S, Hori E, Nabeshima Y, Sasaoka T, Fujimori T, Mori H, Sasahara M. Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury. J Neurochem. 98(2): 588-600. 2006.

49. Hong M, Murai Y, Kutsuna T, Takahashi H, Nomoto K, Cheng CM, Ishizawa S, Zhao QL, Ogawa R, Harmon BV, Tsuneyama K, Takano Y. Suppression of Epstein-Barr nuclear antigen 1 (EBNA1) by RNA interference inhibits proliferation of EBV-positive Burkitt's lymphoma cells. J Cancer Res Clin Oncol. 132(1): 1-8. 2006.

48. Kawaguchi Y, Oya T, Abe Y, Kanamori M, Ishihara H, Yasuda T, Nogami S, Hori T, Kimura T. Spinal stenosis due to the ossified lesions of the lumbar spine. J Neurosurg Spine. 3(4): 262-70. 2005.

47. Yokozawa T, Nakagawa T, Oya T, Okubo T, Juneja LR. Green tea polyphenol and dietary fiber protect against kidney damage in rats with diabetic nephropathy. J Pharm Pharmacol. 57(6): 773-80. 2005.

46. Cheng CM, Tsuneyama K, Matsui K, Takahashi H, Ishizawa S, Takano Y. Cytoplasmic expression of c-erbB2 in non-small cell lung cancers. Virchows Arch. 446(6): 596-603. 2005.

45. Seki S, Kawaguchi Y, Chiba K, Mikami Y, Kizawa H, Oya T, Mio F, Mori M, Miyamoto Y, Masuda I, Tsunoda T, Kamata M, Kubo T, Toyama Y, Kimura T, Nakamura Y, Ikegawa S. A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease. Nat Genet. 37(6): 607-12. 2005.

44. Gao Z, Sasaoka T, Fujimori T, Oya T, Ishii Y, Sabit H, Kawaguchi M, Kurotaki Y, Naito M, Wada T, Ishizawa S, Kobayashi M, Nabeshima YI, Sasahara M. Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing. J Biol Chem. 280(10): 9375-89. 2005.

43. Kashii T, Gomi T, Oya T, Ishii Y, Oda H, Maruyama M, Kobayashi M, Masuda T, Yamazaki M, Nagata T, Tsukada K, Nakajima A, Tatsu K, Mori H, Takusagawa F, Ogawa H, Pitot HC. Some biochemical and histochemical properties of human liver serine dehydratase. Int J Biochem Cell Biol. 37(3): 574-89. 2005.

42. Nogami S, Ishii Y, Kawaguchi M, Sakata N, Oya T, Takagawa K, Kanamori M, Sabit H, Obata T, Kimura T, Sasahara M. ZFH4 protein is expressed in many neurons of developing rat brain. J Comp Neurol. 482(1): 33-49. 2005.

41. Kumada T, Tsuneyama K, Hatta H, Ishizawa S, Takano Y. Improved 1-h rapid immunostaining method using intermittent microwave irradiation: practicability based on 5 years application in Toyama Medical and Pharmaceutical University Hospital. Mod Pathol. 17(9): 1141-9. 2004.

40. Egawa-Tsuzuki T, Ohno M, Tanaka N, Takeuchi Y, Uramoto H, Faigle R, Funa K, Ishii Y, Sasahara M. The PDGF B-chain is involved in the ontogenic susceptibility of the developing rat brain to NMDA toxcity. Exp Neurol. 186(1): 89-98. 2004.

39. Banskota AH, Nguyen NT, Tezuka Y, Le Tran Q, Nobukawa T, Kurashige Y, Sasahara M, Kadota S. Secoisolariciresinol and isotaxiresinol inhibit tumor necrosis factor-alpha-dependent hepatic apoptosis in mice. Life Sci. 74(22): 2781-92. 2004.

38. Nguyen NT, Banskota AH, Tezuka Y, Le Tran Q, Nobukawa T, Kurashige Y, Sasahara M, Kadota S. Hepatoprotective Effect of Taxiresinol and (7'R)-7'-Hydroxylariciresinol on D-Galactosamine and Lipopolysaccharide-Induced Liver Injury in Mice. Planta Med. 70(1): 29-33. 2004.

37. Ishii Y, Kawaguchi M, Takagawa K, Oya T, Nogami S, Tamura A, Miura Y, Ido A, Sakata N, Hashimoto-Tamaoki T, Kimura T, Saito T, Tamaoki T, Sasahara M. ATBF1-A protein, but not ATBF1-B, is preferentially expressed in developing rat brain. J Comp Neurol. 465(1): 57-71. 2003.

36. Masuda T, Ogawa H, Matsushima T, Kawamata S, Sasahara M, Kuroda K, Suzuki Y, Takata Y, Yamazaki M, Takusagawa F, Pitot HC. Localization and hormonal control of serine dehydratase during metabolic acidosis differ markedly from those of phosphoenolpyruvate carboxykinase in rat kidney. Int J Biochem Cell Biol. 35(8): 1234-47. 2003.

35. Takikita-Suzuki M, Haneda M, Sasahara M, Owada MK, Nakagawa T, Isono M, Takikita S, Koya D, Ogasawara K, Kikkawa R. Activation of SRC kinase in platelet-derived growth factor-B-dependent tubular regeneration after acute ischemic renal injury. Am J Pathol. 163(1): 277-86. 2003.

34. Ishizawa S, Slovak ML, Popplewell L, Bedell V, Wrede JE, Carter NH, Snyder DS, Arber DA. High frequency of pro-B acute lymphoblastic leukemia in adults with secondary leukemia with 11q23 abnormalities. Leukemia. 17(6): 1091-5. 2003.

33. Zhao YL, Takagawa K, Oya T, Yang HF, Gao ZY, Kawaguchi M, Ishii Y, Sasaoka T, Owada K, Furuta I, Sasahara M. Active Src expression is induced after rat peripheral nerve injury. Glia. 42(2): 184-93. 2003.

32. Abe Y, Nakamura H, Yoshino O, Oya T, Kimura T. Decreased neural damage after spinal cord injury in tPA-deficient mice. J Neurotrauma. 20(1): 43-57. 2003.

31. Nakagawa T, Yokozawa T, Oya T, Sasahara M, Terasawa K. Evaluation of Keishi-bukuryo-gan in diabetic nephropathy model by comparing with aminoguanidine, butylated hydroxytoluene and captopril. J Trad Med. 19(6): 200-8. 2002.

30. Yokozawa T, Muto Y, Wakaki K, Kashiwagi H. Site of methylguanidine production and factors that influence production levels. Nephron. 92(2): 356-62. 2002.

29. Chu PG, Ishizawa S, Wu E, Weiss LM. Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein. Am J Surg Pathol. 26(8): 978-88. 2002.

28. Matsuno H, Yudoh K, Nakazawa F, Koizumi F. Relationship between histological findings and clinical findings in rheumatoid arthritis. Pathol Int. 52(8): 527-33. 2002.

27. Oya T, Zhao YL, Takagawa K, Kawaguchi M, Shirakawa K, Yamauchi T, Sasahara M. Platelet-derived growth factor-B expression induced after rat peripheral nerve injuries. Glia. 38(4): 303-12. 2002.

26. Teranishi H, Takagawa K, Arai Y, Wakaki K, Sumi Y, Takaya K. Histological Staining of Cadmium with 2-(8-quinolylazo)-4,5-diphenylimidazole (QAI) in the Kidneys of Rats Periorally Exposed to Cadmium. J Occup Health. 44: 60-2. 2002.

25. Matsui K, Takano Y, Yu ZX, Suh Hi JE, Stetler-Stevenson WG, Travis WD, Ferrans VJ. Immunohistochemical study of endothelin-1 and matrix metalloproteinases in plexogenic pulmonary arteriopathy. Pathol Res Pract. 198: 403-12. 2002.

24. Wei L, Murai Y, Okada E, Matsui K, Hayashi S, Horie M, Takano Y. Modified simplified western blotting protocol: use of intermittent microwave irradiation (IMWI) and 5% skim milk to improve binding specificity. Pathol Int. 52: 234-8. 2002.

23. Tran QL, Adnyana IK, Tezuka Y, Harimaya Y, Saiki I, Kurashige Y, Tran QK, Kadota S. Hepatoprotective effect of majonoside R2, the major saponin from Vietnamese ginseng (Panax vietnamensis). Planta Med. 68(5): 402-6. 2002.

22. Kawaguchi M, Miura Y, Ido A, Morinaga T, Sakata N, Oya T, Hashimoto-Tamaoki T, Sasahara M, Koizumi F, Tamaoki T. DNA/RNA-dependent ATPase activity is associated with ATBF1, a multiple homeodomain-zinc finger protein. Biochim Biophys Acta. 1550(2): 164-74. 2001.

21. Yokozawa T, Nakagawa T, Wakaki K, Koizumi F. Animal model of diabetic nephropathy. Exp Toxicol Pathol. 53(5): 359-63. 2001.

20. Murai Y, Dobashi Y, Okada E, Ishizawa S, Shiota M, Mori S, Takano Y. Study on the role of G1 cyclins in Epstein-Barr virus-associated human lymphomas maintained in severe combined immune deficiency (SCID) mice. Int J Cancer. 92(2): 232-9. 2001.

19. Yokoyama M, Amano S, Tsuji A, Sasahara M, Serikawa T, Ihara N, Matsuda M, Hazama F, Handa J. Genetic analysis of cataract in Ihara epileptic rat. Mamm Genome. 12(3): 207-11. 2001.

18. Kataoka H, Miura Y, Joh T, Seno K, Tada T, Tamaoki T, Nakabayashi H, Kawaguchi M, Asai K, Kato T, Itoh M. Alpha-fetoprotein producing cancer lacks transcription factor ATBF1. Oncogene. 20(7): 869-73. 2001.

17. Yamazaki K, Kawai A, Kawaguchi M, Hibino Y, Li F, Sasahara M, Tsukada K, Hiraga K. Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4. Biochem Biophys Res Commun. 280(4): 1077-84. 2001.

16. Ohmori Y, Yoshida T, Okabe M, Takaya K, Koizumi F, Sasahara M. Repeated Antigen Challenge Modulates Expression of Follicular Dendritic Cell (FDC) Related Molecule in Draining Lymph Nodes. Acta Histochem Cytochem. 34(4): 265-73. 2001.

15. Kawai J, Takagawa K, Fujisawa S, Ektessabi A, Hayakawa S. Microbeam XANES and　X-Ray Fluorescence Analysis of Cadmium in Kidney. J Trace and Microprobe Techniques. 19(4): 541-6. 2001.

14. Sakata N, Hemmi K, Kawaguchi M, Miura Y, Noguchi S, Ma D, Sasahara M, Kato T, Hori M, Tamaoki T. The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers. Biochem Biophys Res Commun. 273(2): 686-93. 2000.

13. Minamimura T, Sato H, Kasaoka S, Saito T, Ishizawa S, Takemori S, Tazawa K, Tsukada K. Tumor regression by inductive hyperthermia combined with hepatic embolization using dextran magnetite-incorporated microspheres in rats. Int J Oncol. 16(6): 1153-8. 2000.

12. Nakagawa H, Sasahara M, Haneda M, Koya D, Hazama F, Kikkawa R. Immunohistochemical characterization of glomerular PDGF B-chain and PDGF beta-receptor expression in diabetic rats. Diabetes Res Clin Pract. 48(2): 87-98. 2000.

11. Ishikawa-Nakayama K, Sugiyama E, Sawazaki S, Taki H, Kobayashi M, Koizumi F, Furuta I. Chronic recurrent multifocal osteomyelitis showing marked improvement with corticosteroid treatment. J Rheumatol. 27(5): 1318-9. 2000.

10. Sakai S, Kawamata H, Mantani N, Kogure T, Shimada Y, Terasawa K, Sakai T, Imanishi N, Ochiai H. Therapeutic effect of anti-macrophage inflammatory protein 2 antibody on influenza virus-induced pneumonia in mice. J Virol. 74(5): 2472-6. 2000.

9. Nakagawa T, Sasahara M, Haneda M, Kataoka H, Nakagawa H, Yagi M, Kikkawa R, Hazama F. Role of PDGF B-chain and PDGF receptors in rat tubular regeneration after acute injury. Am J Pathol. 155(5): 1689-99. 1999.

8. Yasuda M, Kawamata T, Komure O, Kuno S, D'Souza I, Poorkaj P, Kawai J, Tanimukai S, Yamamoto Y, Hasegawa H, Sasahara M, Hazama F, Schellenberg GD, Tanaka C. A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration. Neurology. 53(4): 864-8. 1999.

7. Taki H, Sakai T, Sugiyama E, Mino T, Kuroda A, Taki K, Hamazaki T, Koizumi F, Kobayashi M. Monokine stimulation of interleukin-11 production by human vascular smooth muscle cells in vitro. Atherosclerosis. 144(2): 375-80. 1999.

6. Koizumi F, Matsuno H, Wakaki K, Ishii Y, Kurashige Y, Nakamura H. Synovitis in rheumatoid arthritis: scoring of characteristic histopathological features. Pathol Int. 49(4): 298-304. 1999.

5. Ogawa H, Takusagawa F, Wakaki K, Kishi H, Eskandarian MR, Kobayashi M, Date T, Huh NH, Pitot HC. Rat liver serine dehydratase. Bacterial expression and two folding domains as revealed by limited proteolysis. J Biol Chem. 274(18): 12855-60. 1999.

4. Sasahara M, Amano S, Sato H, Yang JG, Hayase Y, Kaneko M, Sato I, Suzaki M, Hazama F. Normal developing rat brain expresses a platelet-derived growth factor B chain (c-sis) mRNA truncated at the 5' end. Oncogene. 16(12): 1571-8. 1998.

3. Sasahara M, Raines EW, Chait A, Carew TE, Steinberg D, Wahl PW, Ross R. Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation? J Clin Invest. 94(1): 155-64. 1994.

2. Sasahara M, Fries JW, Raines EW, Gown AM, Westrum LE, Frosch MP, Bonthron DT, Ross R, Collins T. PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell. 64(1): 217-27. 1991.

1. Ross R, Masuda J, Raines EW, Gown AM, Katsuda S, Sasahara M, Malden LT, Masuko H, Sato H. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science. 248(4958): 1009-12. 1990.

Case Reports

67. Murayama A, Tajiri K, Nakaya A, Ito H, Hayashi Y, Entani T, Nagata K, Tanaka S, Hamashima T, Yasuda I. Intrahepatic Bile Duct Injury as a Hepatic Immune-Related Adverse Event after Immune-Checkpoint Inhibitor Treatment. Case Rep Gastroenterol. 15(3): 645-51. 2021.

66. 山内直岳，濱島 丈，奥野のり子，田中真一，野口 映，鈴木賀代，安田剛敏，井村穣二，長谷川 匡，笹原正清．30年の経過を経て高異型度の領域が出現した末梢神経鞘腫瘍の1例．診断病理．38(3): 285-94. 2021.

65. Takakura H, Hamashima T, Tachino H, Nakazato A, Minato H, Sasahara M, Shojaku H. Clinicopathological Features of Thyroid-Like Low-Grade Nasopharyngeal Papillary Adenocarcinoma: A Case Report and Review of the Literature. Front Surg. 7: 596796. 2020.

64. Furukawa F, Makino T, Takemoto K, Mizawa M, Arita K, Hamashima T, Shimizu T. Sarcoid reactions in the skin caused by mantle cell lymphoma. Eur J Dermato. 30(1): 57-8. 2020.

63. 一松啓介，上村吉穂，江川雅之，奥野のり子，寺畑信太郎．腎Tubulocystic carcinomaの1例．泌尿器科紀要．65(4): 139. 2019.

62. 上村吉穂，一松啓介，江川雅之，奥野のり子，寺畑信太郎，木村圭一．腎静脈内腫瘍塞栓を伴った右腎盂癌の1例．泌尿器科紀要．65(4): 145. 2019.

61. Nishiyama N, Ikehata Y, Okuno N, Sasahara M, Sakamaki I, Yamamoto Y, Kitamura H. A rare case of synchronous bilateral epididymal and testicular metastases of urothelial carcinoma of the bladder after intravesical bacillus Calmette-Guerin. Int Cancer Conf J. 10(1): 59-62. 2020.

60. Imaue S, Tomihara K, Hamashima T, Tomizawa G, Nomura K, Sasahara M, Noguchi M. Successful multimodal treatment of intraoral salivary duct carcinoma in a patient with multiple lymph node metastases: a case report. World J Surg Oncol. 15(1): 18. 2017.

59. Makino T, Ishida W, Hamashima T, Mizawa M, Sasahara M, Shimizu T. An intermediate vascular tumour between kaposiform hemangioendothelioma and tufted angioma with regression of the skin lesion. Eur J Dermatol. 27(2): 175-6. 2017.

58. Yunoki T, Tabuchi Y, Kondo T, Ishii Y, Hayashi A. Overexpression of the anti-apoptotic protein BAG3 in human choroidal melanoma: A case report. Oncol Lett. 13(6): 4169-72. 2017.

57. Hori E, Hayakawa Y, Hayashi T, Hori S, Okamoto S, Shibata T, Kubo M, Horie Y, Sasahara M, Kuroda S. Mobilization of Pluripotent Multilineage-Differentiating Stress-Enduring Cells in Ischemic Stroke. J Stroke Cerebrovasc Dis. 25(6): 1473-81. 2016.

56. Makino T, Hara H, Hamashima T, Mizawa M, Seki Y, Hayashi M, Shimizu T. Hodgkin's lymphoma presenting as subcutaneous masses in the left upper arm. J Dermatol. 43(10): 1244-6. 2016.

55. 下平健太郎，石橋敏光，青木裕一，笹原正清，濱島 丈．S状結腸に穿通した卵巣成熟嚢胞性奇形腫の1例．日本臨床外科学会雑誌. 77(10): 2547-51. 2016.

54. Akashi M, Ando T, Hamashima T, Yoshita H, Nanjo S, Mihara H, Fujinami H, Kajiura S, Nishikawa J, Miura Y, Hosokawa A, Sugiyama T. Multiple Colon Ulcers with Typical Small Intestinal Lesions Induced by Non-Steroidal Anti-Inflammatory Drugs. Intern Med. 54(16): 1995-9. 2015.

53. Matsui K, Makino T, Mizawa M, Hamashima T, Hanakawa H, Hatta N, Sasahara M, Shimizu T. Extramammary Paget's disease occurring in the context of Cowden syndrome: true association or mere coincidence? Eur J Dermatol. 25(1): 89-91. 2015.

52. Tomihara K, Hamashima T, Nagao T, Nakamori K, Sasahara M, Noguchi M. Sarcomatoid salivary duct carcinoma of the palate: a rare case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 119(1): e27-32. 2015.

51. Kawasaki Y, Makimoto M, Nomura K, Hoshino A, Hamashima T, Hiwatari M, Nakazawa A, Takita J, Yoshida T, Kanegane H. Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma. Clinical Case Reports. 3(3): 145-9. 2015.

50. Hoshino A, Nomura K, Hamashima T, Isobe T, Seki M, Hiwatari M, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Takita J, Kanegane H. Aggressive transformation of anaplastic large cell lymphoma with increased number of ALK-translocated chromosomes. Int J Hematol. 101(2): 198-202. 2015.

49. 濱島 丈，石井陽子，山本誠士，名倉里織，深原一晃，芳村直樹，笹原正清．梅毒性大動脈炎の1例．診断病理. 32(1): 46-9. 2015.

48. Seki Y, Makino T, Mizawa M, Hamashima T, Sasahara M, Shimizu T. Immunohistological examination of a skin lesion in a Japanese case with hand, foot and mouth disease caused by coxsackie-virus A6. Eur J Dermatol. 24(4): 506-7. 2014.

47. 田澤賢一，土屋康紀，山岸文範，笹原正清，嶋田 裕，塚田一博．成分分析が可能であった虫垂結石症の2例．外科. 76(7): 787-90. 2014.

46. 田澤賢一，土屋康紀，山岸文範，笹原正清，嶋田 裕，塚田一博．Meckel憩室の索状物による絞扼性腸閉塞の1例．外科. 76(5): 546-9. 2014.

45. Kuroda N, Tanaka A, Yamaguchi T, Kasahara K, Naruse K, Yamada Y, Hatanaka K, Shinohara N, Nagashima Y, Mikami S, Oya M, Hamashima T, Michal M, Hes O. Chromophobe renal cell carcinoma, oncocytic variant: a proposal of a new variant giving a critical diagnostic pitfall in diagnosing renal oncocytic tumors. Med Mol Morphol. 46(1): 49-55. 2013.

44. 田澤賢一，土屋康紀，新保雅宏，山岸文範，笹原正清，塚田一博．経肛門的イレウス管の先端により口側結腸の穿通をきたした閉塞性S状結腸癌の1例．外科. 75(8): 907-10. 2013.

43. 高取俊介，野々目和信，金山雅美，月城孝志，康山俊学，樋口清博，石井陽子，笹原正清．内視鏡的に切除した直腸高分化型神経内分泌腫瘍の1例．ENDOSCOPIC FORUM for digestive disease. 29(1): 62. 2013.

42. 田澤賢一，土屋康紀，山岸文範，津留明彦，笹原正清，塚田一博．白血球減少をきたした卵管卵巣膿瘍破裂の1例．外科. 75(5): 565-8. 2013.

41. 田澤賢一，土屋康紀，山岸文範，林 伸一，笹原正清，塚田一博．術前診断が可能であった虫垂憩室炎の1例．外科. 75(2): 215-7. 2013.

40. 田澤賢一，土屋康紀，新保雅宏，山岸文範，笹原正清，塚田一博．上部消化管造影後11日目に発症したbarium虫垂炎の1例．外科. 75(13): 1510-3. 2013.

39. Inomata M, Hayashi R, Kambara K, Okazawa S, Imanishi S, Ichikawa T, Suzuki K, Yamada T, Miwa T, Kashii T, Matsui S, Tobe K, Sasahara M. Miliary brain metastasis presenting with calcification in a patient with lung cancer: a case report. J Med Case Rep. 6(1): 279. 2012.

38. 舘野宏彦, 安村佐都紀, 將積日出夫, 西田 悠, 渡辺行雄, 高野康雄, 福岡順也, 石井陽子. 高齢発症の鼻腔原発胞巣型横紋筋肉腫剖検例．耳鼻咽喉科臨床. 134: 70-5. 2012.

37. 田村賢太郎，吉田丈俊，堀川 慎二郎，東山弘幸，濱島 丈，石澤 伸，伊藤実香，島 友子，米田 哲，塩崎有宏，齋藤 滋，宮脇利男．胎盤内絨毛癌により胎児母体間輸血症候群を発症した二絨毛膜二羊膜性双胎の1例．周産期医学. 40: 273-6. 2010.

36. 濱島 丈，尾矢剛志，石井陽子，申 杰，石澤 伸，笹原正清．皮下嚢胞として発症した類血管腫型線維性組織球腫の1例．診断病理. 26: 62-7. 2009.

35. Nagai S, Kurimoto M, Ishizawa S, Hayashi N, Hamada H, Kamiyama H, Endo S. A rare astrocytic tumor with rhabdoid features. Brain Tumor Pathol. 26(1): 19-24. 2009.

34. Kanegane H, Nomura K, Abe A, Makino T, Ishizawa S, Shimizu T, Naoe T, Miyawaki T. Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastosytosis. Int J Hematol. 89(1): 86-90. 2009.

33. Tsunekawa S, Ohi Y, Ishii Y, Sasahara M, Haji A. Hypoxic Ventilatory Response in Platelet-Derived Growth Factor Receptor- s -Knockout Mice. J Pharmacol Sci. 110: 270-5. 2009.

32. Shiozaki A, Yoneda N, Yoneda S, Soeda Y, Hamashima T, Ishizawa S, Tamura K, Horikawa S, Higashiyama H, Yoshida T, Miyawaki T, Saito S. Gestational choriocarcinoma in one placenta of dichorionic diamniotic twins who showed severe anemia. Placenta. 30: 821. 2009.

31. Ogawa J, Kanegane H, Tsuneyama K, Kanezaki R, Futatani T, Nomura K, Ishizawa S, Sasahara M, Ito E, Miyawaki T. Platelet-derived growth factor may be associated with fibrosis in a Down syndrome patient with transient myeloproliferative disorder. Eur J Haematol. 81(1): 58-64. 2008.

30. Kuroda K, Ishizawa S, Kudo T, Uotani H, Hosokawa A, Tanaka T, Kitano H, Hori T, Tsukada K, Sugiyama T, Fukuoka J. Localized malignant mesenteric mesothelioma causing small bowel obstruction. Pathol Int. 58(4): 239-43. 2008.

29. Yasuda T, Kanamori M, Ishizawa S, Nogami S, Hori T, Suzuki K, Osada R, Kimura T. Multicentric diffuse-type giant cell tumor of the hand. Mod Rheumatol. 18(1): 67-71. 2008.

28. Otsubo K, Kanegane H, Nomura K, Miyawaki T, Ishizawa S. Atypical lymphoproliferative disorder in a patient with X-linked thrombocytopenia. Pediatr Blood Cancer. 51: 443-4. 2008.

27. Tsuboi Y, Hayashi N, Kurimoto M, Nagai S, Sasahara M, Endo S. Malignant transformation of clival chordoma after gamma knife surgery. Neurol Med Chir. 47(10): 479-82. 2007.

26. Hori E, Kurimoto M, Fukuda O, Takahashi C, Nagai S, Oya T, Endo S. Recurrent intracranial solitary fibrous tumor initially diagnosed as hemangiopericytoma. Brain Tumor Pathol. 24(1): 31-4. 2007.

25. Morii A, Furuya Y, Fujiuchi Y, Akashi T, Ishizawa S, Fuse H. Urachal signet ring cell carcinoma. Int J Urol. 14(4): 360-1. 2007.

24. Kawamura S, Nakamura T, Oya T, Ishizawa S, Sakai Y, Tanaka T, Saito S, Fukuoka J. Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy. Pathol Int. 57(4): 213-8. 2007.

23. Tajiri K, Shimizu Y, Mihara H, Kawanishi Y, Orihara T, Takahashi H, Ishizawa S, Kawai S, Sugiyama T. Cholangiocarcinoma at the cystic duct discovered by lymph node metastases with clear cell transformation. Intern Med. 45(18): 1045-8. 2006.

22. Tsuda M, Ichiki K, Doki Y, Usuda K, Misaki T, Arai N, Shimizu M, Oya T. Mediastinal lymph node metastasis of thyroid cancer occurring 15 years after the initial operation; report of a case. Kyobu Geka. 59(6): 487-90. 2006.

21. 坂東 正，北條荘三，渡辺智子，遠藤暢人，横山義信，野澤聡志，山岸文範，塚田一博，石澤 伸．動注化学療法後肝切除を施行し長期生存が得られたファーター乳頭部癌肝転移再発の1例．日本消化器外科学会．39: 481-5. 2006.

20. 田澤賢一，高橋博之，山岸文範，塚田一博，石澤 伸．S状結腸狭窄を呈した群発型左側腸憩室炎の一例．外科．67: 712-4. 2005.

19. 朴木久恵，荒屋 潤，高野敦子，石澤 伸，多喜博文．肺浸潤影を伴った好酸球性筋炎(好酸球性多発性筋炎)の一例．中部リウマチ．36: 64-5. 2005.

18. 今村朋理，渡部明彦，明石拓也，十二町 明，水野一郎，永川 修，布施秀樹，石澤 伸．腎部分切除術を施行したtubulopapillary adenomaの一例．泌尿器外科．18: 59-62. 2005.

17. Kominato Y, Matsui K, Hata Y, Matsui K, Kuwayama N, Ishizawa S, Takizawa H. Acute subdural hematoma due to arteriovenous malformation primarily in dura mater: a case report. Leg Med (Tokyo). 6(4): 256-60. 2004.

16. Oshima Y, Kawaguchi S, Nagoya S, Wada T, Kokai Y, Ikeda T, Nogami S, Oya T, Hirayama Y. Abdominal small round cell tumor with osteoid and EWS/FLI1. Hum Pathol. 35(6): 773-5. 2004.

15. Yata Y, Nakayama Y, Takahara T, Yamazaki K, Masuyama K, Sawataishi M, Suzuki S, Honma M, Ishizawa S, Tanaka M, Watanabe A, Sugiyama T. A case of small cell gastric carcinoma with an adenocarcinoma component operated curatively. Acta Med Okayama. 58(6): 275-8. 2004.

14. Andou T, Shinagawa K, Nanbu S, Shimizu Y, Atarashi Y, Minemura M, Higuchi K, Watanabe A, Takagawa K. An old woman case of autoimmune hepatitis presenting with fluminant hepatic failure. Nippon Shokakibyo Gakkai Zasshi. 100(3): 344-8. 2003.

13. Nagashima T, Cao B, Takeuchi N, Chuma T, Mano Y, Fujimoto M, Nunomura M, Oshikiri T, Miyazaki K, Dohke M, Kashimura N, Shinohara T, Orba Y, Ishizawa S, Nagashima K. Clinicopathological studies of peripheral neuropathy in Churg-Strauss syndrome. Neuropathology. 22(4): 299-307. 2002.

12. Asahi T, Kurimoto M, Kawaguchi M, Yamamoto N, Sato S, Endo S. Malignant fibrous histiocytoma originating at the site of a previous fronto-temporal craniotomy. J Clin Neurosci. 9(6): 704-8. 2002.

11. 野上重治，笹原正清，尾矢剛志，山岸文範，金森昌彦．類骨形成を認めた腹腔内内部肉腫の一例．東海骨軟部腫瘍．14: 37-8. 2002.

10. 高橋博之，林 伸一，松井一裕，高野康雄．Kasabach-Merritt 症候群の若年女性に発症した肺intravascular papillary endothelial hyperplasia(IPEH) の１例．診断病理．19(4): 315-8. 2002.

9. Uotani H, Hirokawa S, Saito F, Tauchi K, Shimoda M, Ishizawa S, Kawaguchi M, Nomura K, Kanegane H, Tsukada K. Non-Hodgkin's lymphoma of the ascending colon in a patient with becker muscular dystrophy: report of a case. Surg Today. 31(11): 1016-9. 2001.

8. Okamoto S, Kurimoto M, Hirashima Y, Hayashi N, Kuwayama N, Endo S, Okada E, Ishizawa S. Systemic non-Hodgkin lymphoma initially presented with visual disturbance due to intrasellar lymphoma--a case report. No Shinkei Geka. 29(1): 59-63. 2001.

7. 田澤賢一，高橋博之，山岸文範，鈴木修一郎，清水哲朗，塚田一博，高川 清，石澤 伸．軟骨化生を伴った乳癌の１例．臨床外科．56: 117-20. 2001.

6. 石井陽子，若木邦彦，石澤 伸，木屋千恵子，斉藤勝彦，笹原正清．直腸原発杯細胞カルチノイドの１例．日本臨床細胞学会雑誌．40(6): 616-21. 2001.

5. 田澤賢一，高橋博之，山岸文範，鈴木修一郎，清水哲朗，塚田一博，高川 清，石澤 伸．軟骨化生を伴った乳癌の１例．臨床外科．56: 117-20. 2001.

4. Matsui H, Kanamori M, Abe Y, Sakai T, Wakaki K. Multifocal clear cell meningioma in the spine: a case report. Neurosurg Rev. 21(2-3): 171-3. 1998.

3. Matsui H, Kanamori M, Yudoh K, Ohmori K, Yasuda T, Wakaki K. Cystic spinal cord tumors: magnetic resonance imaging correlated to histopathological findings. Neurosurg Rev. 21(2-3): 147-51. 1998.

2. Sugiyama S, Murakami A, Yokokawa M, Misaki T, Wakaki K. Internal jugular vein malformation with mature adipose deposits in the mediastinum. Surg Today. 28(4): 455-8. 1998.

1. Nagaki Y, Hayasaka S, Honma M. Idiopathic sclerosing inflammation of the upper eyelid. Ophthalmologica. 212(5): 339-43. 1998.