講座メンバー

鈴木(大久保)玲子 Reiko Okubo-Suzuki
特命助教 (Specially Appointed Assistant Professor)

現在の研究テーマ(current research project)

記憶における神経回路・神経細胞集団の役割の解析

抱負(ambitious future plan)

人類に貢献できる研究成果を残したい。

専門分野 (background scientific field)

分子細胞生物学、神経科学

略 歴(personal history)

1993-1997 創価大学工学部生物工学科
1997-1999 創価大学大学院工学研究科生物工学専攻(工学修士)
1999-2003 創価大学生命科学研究所 技術員
2003-2008 横浜国立大学環境情報学府環境生命学専攻(工学博士)
2008-2009 三菱化学生命科学研究所 特別研究員
2009-現在 富山大学医学部生化学講座 特命助教

業 績(publications)

  • Yokose J, Okubo-Suzuki R, Nomoto M, Ohkawa N, Nishizono H, Suzuki A, Matsuo M, Tsujimura S, Takahashi Y, Nagase M, Watabe AM, Sasahara M, Kato F, Inokuchi K. Overlapping memory trace indispensable for linking, but not recalling, individual memories. Science. Jan 27;355(6323):398-403, 2017
  • Okubo-Suzuki R, Saitoh Y, Shehata M, Zhao Q, Enomoto H, Inokuchi K. Frequency-specific stimulations induce reconsolidation of long-term potentiation in freely moving rats. Mol Brain. Mar 25;9:36, 2016
  • Tsubota T, Okubo-Suzuki R, Ohashi Y, Tamura K, Ogata K, Yaguchi M, Matsuyama M, Inokuchi K, Miyashita Y. Cofilin1 controls transcolumnar plasticity in dendritic spines in adult barrel cortex. PLoS Biol. Feb 27;13(2):e10020, 2015
  • Shehata M, Matsumura H, Okubo-Suzuki R, Ohkawa N, Inokuchi K. Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. J Neurosci. Jul 25;32(30):10413-22, 2012
  • Kitamura T, Okubo-Suzuki R, Takashima N, Murayama A, Hino T, Nishizono H, Kida S, Inokuchi K. Hippocampal function is not required for the precision of remote place memory. Mol Brain. Feb 2;5:5, 2012
  • Okubo-Suzuki R, Okada D, Sekiguchi M, Inokuchi K. Synaptopodin maintains the neural activity-dependent enlargement of dendritic spines in hippocampal neurons. Mol Cell Neurosci. 38(2):266-76, 2008
  • Sasaki N, Manya H, Okubo R, Kobayashi K, Ishida H, Toda T, Endo T, Nishihara S. beta4GalT-II is a key regulator of glycosylation of the proteins involved in neuronal development. Biochem Biophys Res Commun. 333(1):131-7, 2005
  • Ishida H, Togayachi A, Sakai T, Iwai T, Hiruma T, Sato T, Okubo R, Inaba N, Kudo T, Gotoh M, Shoda J, Tanaka N, Narimatsu H. A novel beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T8), which synthesizes poly-N-acetyllactosamine, is dramatically upregulated in colon cancer. FEBS Lett. 579(1):71-8, 2005
  • Kamiyama S, Suda T, Ueda R, Suzuki M, Okubo R, Kikuchi N, Chiba Y, Goto S, Toyoda H, Saigo K, Watanabe M, Narimatsu H, Jigami Y, Nishihara S. Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter. J Biol Chem. 278(28):25958-63,2003
  • Takemae H, Ueda R, Okubo R, Nakato H, Izumi S, Saigo K, Nishihara S. Proteoglycan UDP-galactose:beta-xylose beta 1,4-galactosyltransferase I is essential for viability in Drosophila melanogaster. J Biol Chem. 278(18):15571-8, 2003
  • Togayachi A, Akashima T, Ookubo R, Kudo T, Nishihara S, Iwasaki H, Natsume A, Mio H, Inokuchi J, Irimura T, Sasaki K, Narimatsu H. Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids. J Biol Chem. 276(25):22032-40, 2001
  • Nakayama F, Nishihara S, Iwasaki H, Kudo T, Okubo R, Kaneko M, Nakamura M, Karube M, Sasaki K, Narimatsu H. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV. J Biol Chem. 276(19):16100-6, 2001

趣味・特技(hobby, specialty)

バイオリンの演奏