ハイパードライヒト乾燥羊膜
（HD羊膜）の研究開発について

業績

2020年

原著

  1. Fathy M, Okabe M, Saad Eldien HM, Yoshida T. AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF- β /Smad Signaling Pathway in Rats. Molecules. 2020 Jan 15; 25(2): 348. doi: 10.3390/molecules25020348.
  2. Fathy M, Okabe M, M Othman E, Saad Eldien HM, Yoshida T. Preconditioning of Adipose-Derived Mesenchymal Stem-Like Cells with Eugenol Potentiates Their Migration and Proliferation In Vitro and Therapeutic Abilities in Rat Hepatic Fibrosis. Molecules. 2020 Apr 26; 25(9): 2020. doi: 10.3390/molecules25092020.
  3. Oba J, Okabe M, Yoshida T, Soko C, Fathy M, Amano K, Kobashi D, Wakasugi M, Okudera H. Hyperdry human amniotic membrane application as a wound dressing for a full-thickness skin excision after a third-degree burn injury. Burns Trauma. 2020 Jul 27; 8: tkaa014. doi: 10.1093/burnst/tkaa014. eCollection 2020.

特許申請

  1. 岡部素典，吉田淑子，林　京子，荒川雅彦，inventors; 岡部素典，吉田淑子，林　京子，サクラ精機（株），assignee. ウイルスの不活化方法．特願2020-012404. 20200129.

2021年

著書

  1. 吉田淑子，岡部素典．HORMONE FRONTER IN GYNECOLOGY. 日本：メディカルレビュー社；2021 Sep．胎盤と再生医療—卵膜を含む—；p. 43-50.

原著

  1. Zukawa M, Okabe M, Osada R, Makino H, Nogami M, Seki S, Yoshida T, Kimura T, Kawaguchi Y. Effect of hyperdry amniotic membrane in preventing tendon adhesion in a rabbit model. J Orthop Sci. 2021 Apr 28; S0949-2658(21): 122-126., doi: 10.1016/j.jos.2021.03.005.
  2. Abdel-Hamid NM, Fathy M, Koike C, Yoshida T, Okabe M, Zho K, Abouzied M, Nikaido T. Identification of Chemo and Radio-Resistant Sub-Population of Stem Cells in Human Cervical Cancer HeLa Cells. Cancer Invest. 2021 Sep; 39(8): 661-674., doi:10.1080/07357907.2021.1931875. Epub 2021 Jul 8.
  3. Koike N, Sugimoto J, Okabe M, Arai K, Nogami M, Okudera H, Yoshida T. Distribution of Amniotic Stem Cells in Human Term Amnion Membrane. Microscopy (Oxf). 2021 Sep 18; edfab035. doi: 10.1093/jmicro/dfab035.

2022年

原著

  1. Kumiko Fujiwara , Hiroaki Tsuno , Motonori Okabe , Toshiko Yoshida , Shuichi Imaue , Kei Tomihara, Naoya Arai , Makoto Noguchi, Clinical Application of Hyperdry Amniotic Membrane in Cleft Palate Repair., The Cleft Palate Craniofacial Journal, 2022, doi: 10.1177/10556656221075937
  2. Arai Kenichi, Okabe Motonori, Kobashi Daisuke, Ichimura Kenji, Fathy Moustafa, Oba Jiro, Furuichi Etsuko, Yoshida Satoshi, Yoshida Toshiko, Importance of Housekeeping Gene Optimization for the Analysis of mRNA Expression During Wound Healing in a Third-Degree Burn Injury Model, Journal of burn care & research : official publication of the American Burn Association, 2023, 44, 146 – 157
  3. Amano Koji, Okabe Motonori, Yoshida Toshiko, Oba Jiro, Yoshid Satoshi, Wakasugi Masahiroe, Usui Akihiro, Nakata Yasuki, Okudera Hiroshi, Hyperdry Human Amniotic Membrane as a Protective Dressing for Open Wounds With Exposed Bowel in Mice, Journal of Surgical Research, 2023, 283, 898 - 913

特許取得

  1. 特許第7202582号、乾燥羊膜におけるウイルスの不活化方法、発明者：岡部素典、吉田淑子、林　京子、荒川雅彦、出願人：岡部素典、吉田淑子、林　京子、サクラ精機株式会社、出願日：令和3年1月26日(2021.1.26)

2023年

原著

  1. Kenichi Arai, Motonori Okabe, Daisuke Kobashi, Kenji Ichimura, Moustafa Fathy, Jiro Oba, Etsuko Furuichi, Satoshi Yoshida, Toshiko Yoshida. Importance of Housekeeping Gene Optimization for the Analysis of mRNA Expression During Wound Healing in a Third-Degree Burn Injury Model. Journal of burn care & research : official publication of the American Burn Association. 2023 Jan 5; 44(1): 146-157. doi: 10.1093/jbcr/irac161.
  2. Koji Amano, Motonori Okabe, Toshiko Yoshida, Jiro Oba, Satoshi Yoshida, Masahiro Wakasugi, Akihiro Usui, Yasuki Nakata, Hiroshi Okudera. Hyperdry Human Amniotic Membrane as a Protective Dressing for Open Wounds With Exposed Bowel in Mice. Journal of Surgical Research. 2023 Mar; 283: 898-913. doi: 10.1016/j.jss.2022.09.028.

特許取得

  1. 吉田淑子, 岡部素典, 長田龍介, 頭川峰志, 荒川雅彦, inventors; 富山大学, サクラ精機株式会社, assignee. 腱・腱鞘の再生・修復材およびその使用. 特許7219903号. 2023 Feb 1.
  2. 天野浩司, 吉田淑子, 岡部素典, 相古千加, 荒川雅彦, inventors; 富山大学, サクラ精機株式会社, assignee. 創傷接触部材. 特許7336784号. 2023 Aug 24.

2024年

原著

    なし

特許取得

  1. ToshikoYoshida, Toyama(JP);Motonori Okabe, Toyama(JP);RyusukeOsada, Toyama(JP);Mineyuki Zukawa, Toyama(JP);Masahiko Arakawa, Nagano(JP),Assignees:ToshikoYoshida, Toyama(JP);Motonori Okabe, Toyama(JP);RyusukeOsada, Toyama(JP); Mineyuki Zukawa, Toyama(JP);SAKURA SEIKICO.,LTD., Nagano(JP)　「REGENERATIONOFTENDONAND TENDON SHEATH,RESTORATION MATERIAL,ANDUSEOFRESTORATION MATERIAL」US 12,246,109B2, 20250311

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