Department of Pathology,
Faculty of Medicine,
Academic Research Division
University of Toyama
Bridging Science and Medicine for a Healthier Tomorrow
Welcome to Our Lab
At the Toyama University Department of Pathology and Experimental Medicine,we connect groundbreaking research directly with clinical practice. Our laboratory brings together dedicated researchers, clinicians, and students from medicine,biology, and engineering fields, creating an interdisciplinary and international research environment.
“Our doors are open to everyone driven by curiosity and passion
for advancing healthcare through science.”
— Prof. Katsuyoshi Takata
Our Research Areas
We explore diseases at molecular, cellular, and clinical levels to improve diagnosis, treatment, and understanding of various medical conditions.
Molecular pathogenesis of Hematologic Malignancies
We investigate the molecular mechanisms underlying hematologic malignancies, with a particular focus on intractable lymphomas. Our research explores the associations between tumor genomic alterations and the tumor microenvironment to uncover how tumor cells tumor cells develop and progress. We also aim to identify novel biomarkers that can improve pathological diagnosis and guide treatment strategies.
Generation of Targeted Therapy for relapse/refractory Lymphomas
For lymphomas that do not respond to current standard therapies, we are developing novel therapeutic approaches that target specific tumor antigens. Our goal is to establish more effective treatments for these difficult-to-treat cases and ultimately improve patient outcomes.
Integrated Diagnostics for Hematologic malignancies
We conduct integrated diagnostics and clinicopathological analyses in the field of lymphoma diagnosis, where precision is essential. Our approach incorporates flow cytometry, immunohistochemistry, and genetic analysis to ensure accurate and comprehensive evaluations.
Pathophysiological study in Blood Vessels and Lymphatic Vessels
Blood vessels and lymphatic vessels are essential systems for many organs in the mammalian bodies. Our research seeks to clarify the underlying molecular mechanisms of normal development and disease-related changes in the blood vessels and lymphatic vessels. By our research, novel molecules that are involved in the development of blood vessels and lymphatic vessels are identified, it will be considered as potential therapeutic targets.
Neuro–Vascular Interactions in the CNS
The central nervous system possesses a highly dense vascular networks that plays crucial roles in the brain function. Recent studies have shown that adult neural stem cells anatomically located besides with cerebral blood vessels. Our study aims to uncover the molecular interactions between neural stem cells and the cerebral vasculature.
Drug Discovery Research for Rare and Intractable Diseases
Cystic lymphangioma, a designated rare pediatric disease, currently lacks effective treatments in the clinical setting. Our study is to unravel its underlying molecular mechanisms and develop effective drugs that are targeting the molecules involved in the disease progression. Through this research, we hope to contribute to improved quality of life for patients with cystic lymphangioma.
Role of PDGFR in Developing Brain
Using knockout mouse models, we study the functions of platelet-derived growth factor receptors (PDGFR), which are expressed in various cell types. Our research explores how PDGFR influences glial cell differentiation, neural stem cell behavior, and the role of perivascular cells during brain development.
Recent Highlights
- Presented findings on the tumor microenvironment in pancreatic cancer at the Annual Meeting of the Japanese Society of Pathology (2024).
- Published significant research on molecular diagnostics in international scientific journals.
Why Choose Our Lab?
Strong Clinical Connections
Close collaboration with Toyama University Hospital enhances the clinical relevance and direct applicability of our research.
International & Interdisciplinary Environment
Encouraging collaborations among diverse academic and cultural backgrounds.
Comprehensive Training & Mentorship
Individualized guidance on laboratory techniques, scientific communication, and career development.
Student Testimonials
“Coming from an engineering background, I was initially unsure about joining a medical research team. However, the supportive atmosphere and interdisciplinary collaboration made my experience incredibly rewarding.”
— Yosei Kato, Department of Life Sciences and Bioengineering, Faculty of Engineering (4th year)
Opportunities for Collaboration
We warmly welcome collaboration proposals in
- Tumor microenvironment research
- Infectious disease mechanisms and diagnostics
- Molecular pathology and genetic diagnostics
- Immunopathology research
Recent Collaborators:
- XYZ University, USA (Histopathological Imaging)
- National Institute of Infectious Diseases (Viral Immunopathology)
Life in Toyama
Experience life in Toyama, a peaceful and welcoming city surrounded by nature, offering an excellent quality of life, affordable living, and comprehensive support for international researchers and students.
Join Us
- Contact Form: [Google Form Link for English Inquiries]